Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI020015-14
Application #
2061080
Study Section
Special Emphasis Panel (NSS)
Project Start
1983-06-01
Project End
1998-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Washington University
Department
Physiology
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Barbieri, M A; Ramkumar, T P; Fernadez-Pol, S et al. (2004) Receptor tyrosine kinase signaling and trafficking--paradigms revisited. Curr Top Microbiol Immunol 286:1-20
Barbieri, M Alejandro; Fernandez-Pol, Sebastian; Hunker, Christine et al. (2004) Role of rab5 in EGF receptor-mediated signal transduction. Eur J Cell Biol 83:305-14
Barbieri, M Alejandro; Kong, Chen; Chen, Pin-I et al. (2003) The SRC homology 2 domain of Rin1 mediates its binding to the epidermal growth factor receptor and regulates receptor endocytosis. J Biol Chem 278:32027-36
Cordero, Julia B; Cozzolino, Mario; Lu, Yan et al. (2002) 1,25-Dihydroxyvitamin D down-regulates cell membrane growth- and nuclear growth-promoting signals by the epidermal growth factor receptor. J Biol Chem 277:38965-71
Wilkowsky, S E; Barbieri, M A; Stahl, P D et al. (2002) Regulation of Trypanosoma cruzi invasion of nonphagocytic cells by the endocytically active GTPases dynamin, Rab5, and Rab7. Biochem Biophys Res Commun 291:516-21
Barbieri, M A; Heath, C M; Peters, E M et al. (2001) Phosphatidylinositol-4-phosphate 5-kinase-1beta is essential for epidermal growth factor receptor-mediated endocytosis. J Biol Chem 276:47212-6
Tall, G G; Barbieri, M A; Stahl, P D et al. (2001) Ras-activated endocytosis is mediated by the Rab5 guanine nucleotide exchange activity of RIN1. Dev Cell 1:73-82
Barbieri, M A; Gumusboga, A; Roberts, R L et al. (2001) Measurement of Rab5 protein kinase B/akt and regulation of ras-activated endocytosis. Methods Enzymol 329:145-56
Ricard, C S; Jakubowski, J M; Verbsky, J W et al. (2001) Drosophila rab GDI mutants disrupt development but have normal Rab membrane extraction. Genesis 31:17-29
Barbieri, M A; Roberts, R L; Gumusboga, A et al. (2000) Epidermal growth factor and membrane trafficking. EGF receptor activation of endocytosis requires Rab5a. J Cell Biol 151:539-50

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