Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI020067-13
Application #
2061110
Study Section
Special Emphasis Panel (NSS)
Project Start
1982-09-15
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1998-06-30
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Health Science Center Houston
Department
Internal Medicine/Medicine
Type
Schools of Dentistry
DUNS #
City
Houston
State
TX
Country
United States
Zip Code
77225
Krushkal, J; Bat, O; Gigli, I (2000) Evolutionary relationships among proteins encoded by the regulator of complement activation gene cluster. Mol Biol Evol 17:1718-30
Krushkal, J; Kemper, C; Gigli, I (1998) Ancient origin of human complement factor H. J Mol Evol 47:625-30
Zipfel, P F; Kemper, C; Dahmen, A et al. (1996) Cloning and recombinant expression of a barred sand bass (Paralabrax nebulifer) cDNA. The encoded protein displays structural homology and immunological crossreactivity to human complement/cofactor related plasma proteins. Dev Comp Immunol 20:407-16
Schmitz, J; Zimmer, J P; Kluxen, B et al. (1995) Antibody-dependent complement-mediated cytotoxicity in sera from patients with HIV-1 infection is controlled by CD55 and CD59. J Clin Invest 96:1520-6
Dahmen, A; Kaidoh, T; Zipfel, P F et al. (1994) Cloning and characterization of a cDNA representing a putative complement-regulatory plasma protein from barred sand bass (Parablax neblifer). Biochem J 301 ( Pt 2):391-7
Barrett, K E; Yen, A; Bigby, T D et al. (1994) Inhibition of human peripheral blood lymphocyte function by protoporphyrin and longwave ultraviolet light. J Immunol 153:3286-94
Dovezenski, N; Billetta, R; Gigli, I (1992) Expression and localization of proteins of the complement system in human skin. J Clin Invest 90:2000-12
Tausk, F; Gigli, I (1990) The human C3b receptor: function and role in human diseases. J Invest Dermatol 94:141S-145S
Reed, S L; Gigli, I (1990) Lysis of complement-sensitive Entamoeba histolytica by activated terminal complement components. Initiation of complement activation by an extracellular neutral cysteine proteinase. J Clin Invest 86:1815-22
Kaidoh, T; Gigli, I (1989) Phylogeny of the plasma regulatory proteins of the complement system. Prog Clin Biol Res 297:199-209

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