Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI021017-20
Application #
6627966
Study Section
Special Emphasis Panel (NSS)
Program Officer
Schaefer, Michael R
Project Start
1983-09-01
Project End
2005-01-31
Budget Start
2003-02-01
Budget End
2004-01-31
Support Year
20
Fiscal Year
2003
Total Cost
$380,746
Indirect Cost
Name
University of Kentucky
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
939017877
City
Lexington
State
KY
Country
United States
Zip Code
40506
Fowler, Janet M; Wulff, Christine R; Straley, Susan C et al. (2009) Growth of calcium-blind mutants of Yersinia pestis at 37 degrees C in permissive Ca2+-deficient environments. Microbiology 155:2509-21
Philipovskiy, Alexander V; Cowan, Clarissa; Wulff-Strobel, Christine R et al. (2005) Antibody against V antigen prevents Yop-dependent growth of Yersinia pestis. Infect Immun 73:1532-42
Cowan, Clarissa; Philipovskiy, Alexander V; Wulff-Strobel, Christine R et al. (2005) Anti-LcrV antibody inhibits delivery of Yops by Yersinia pestis KIM5 by directly promoting phagocytosis. Infect Immun 73:6127-37
Wulff-Strobel, Christine R; Williams, Andrew W; Straley, Susan C (2002) LcrQ and SycH function together at the Ysc type III secretion system in Yersinia pestis to impose a hierarchy of secretion. Mol Microbiol 43:411-23
Cowan, C; Jones, H A; Kaya, Y H et al. (2000) Invasion of epithelial cells by Yersinia pestis: evidence for a Y. pestis-specific invasin. Infect Immun 68:4523-30
Fields, K A; Straley, S C (1999) LcrV of Yersinia pestis enters infected eukaryotic cells by a virulence plasmid-independent mechanism. Infect Immun 67:4801-13
Payne, P L; Straley, S C (1999) YscP of Yersinia pestis is a secreted component of the Yop secretion system. J Bacteriol 181:2852-62
Fields, K A; Nilles, M L; Cowan, C et al. (1999) Virulence role of V antigen of Yersinia pestis at the bacterial surface. Infect Immun 67:5395-408
Payne, P L; Straley, S C (1998) YscO of Yersinia pestis is a mobile core component of the Yop secretion system. J Bacteriol 180:3882-90
Williams, A W; Straley, S C (1998) YopD of Yersinia pestis plays a role in negative regulation of the low-calcium response in addition to its role in translocation of Yops. J Bacteriol 180:350-8

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