Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI025328-15
Application #
6510381
Study Section
Special Emphasis Panel (NSS)
Program Officer
Sharma, Opendra K
Project Start
1987-09-01
Project End
2006-03-31
Budget Start
2002-04-01
Budget End
2003-03-31
Support Year
15
Fiscal Year
2002
Total Cost
$417,675
Indirect Cost

  Institution

Name
Harvard University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115

  Publications

Martinez-Navio, Jose M; Desrosiers, Ronald C (2012) Neutralizing capacity of monoclonal antibodies that recognize peptide sequences underlying the carbohydrates on gp41 of simian immunodeficiency virus. J Virol 86:12484-93
Yuste, Eloisa; Bixby, Jacqueline; Lifson, Jeffrey et al. (2008) Glycosylation of gp41 of simian immunodeficiency virus shields epitopes that can be targets for neutralizing antibodies. J Virol 82:12472-86
Laird, Melissa E; Igarashi, Tatsuhiko; Martin, Malcolm A et al. (2008) Importance of the V1/V2 loop region of simian-human immunodeficiency virus envelope glycoprotein gp120 in determining the strain specificity of the neutralizing antibody response. J Virol 82:11054-65
Mansfield, Keith; Lang, Sabine M; Gauduin, Marie-Claire et al. (2008) Vaccine protection by live, attenuated simian immunodeficiency virus in the absence of high-titer antibody responses and high-frequency cellular immune responses measurable in the periphery. J Virol 82:4135-48
Sato, Shuji; Yuste, Eloisa; Lauer, William A et al. (2008) Potent antibody-mediated neutralization and evolution of antigenic escape variants of simian immunodeficiency virus strain SIVmac239 in vivo. J Virol 82:9739-52
Laird, Melissa E; Desrosiers, Ronald C (2007) Infectivity and neutralization of simian immunodeficiency virus with FLAG epitope insertion in gp120 variable loops. J Virol 81:10838-48
Pikora, Cheryl A; Wittish, Christine; Desrosiers, Ronald C (2006) p6gag of human and simian immunodeficiency viruses is tolerant to small in-frame deletions downstream of the late domain. Virology 346:479-89
Pikora, Cheryl; Wittish, Christine; Desrosiers, Ronald C (2005) Identification of two N-linked glycosylation sites within the core of the simian immunodeficiency virus glycoprotein whose removal enhances sensitivity to soluble CD4. J Virol 79:12575-83
Swigut, Tomek; Alexander, Louis; Morgan, Jennifer et al. (2004) Impact of Nef-mediated downregulation of major histocompatibility complex class I on immune response to simian immunodeficiency virus. J Virol 78:13335-44
Alexander, Louis; Illyinskii, Petr O; Lang, Sabine M et al. (2003) Determinants of increased replicative capacity of serially passaged simian immunodeficiency virus with nef deleted in rhesus monkeys. J Virol 77:6823-35

Showing the most recent 10 out of 69 publications