Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI028724-14
Application #
6838727
Study Section
Special Emphasis Panel (NSS)
Program Officer
Rogers, Martin J
Project Start
1989-07-01
Project End
2008-12-31
Budget Start
2005-01-01
Budget End
2005-12-31
Support Year
14
Fiscal Year
2005
Total Cost
$558,179
Indirect Cost
Name
University of Pennsylvania
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Shukla, Anurag; Olszewski, Kellen L; Llinás, Manuel et al. (2018) Glycolysis is important for optimal asexual growth and formation of mature tissue cysts by Toxoplasma gondii. Int J Parasitol 48:955-968
Beiting, Daniel P; Hidano, Shinya; Baggs, Julie E et al. (2015) The Orphan Nuclear Receptor TLX Is an Enhancer of STAT1-Mediated Transcription and Immunity to Toxoplasma gondii. PLoS Biol 13:e1002200
Lynch, Michael; Field, Mark C; Goodson, Holly V et al. (2014) Evolutionary cell biology: two origins, one objective. Proc Natl Acad Sci U S A 111:16990-4
Beiting, Daniel P; Peixoto, Lucia; Akopyants, Natalia S et al. (2014) Differential induction of TLR3-dependent innate immune signaling by closely related parasite species. PLoS One 9:e88398
Ouologuem, Dinkorma T; Djimdé, Abdoulaye A; Diallo, Nouhoum et al. (2013) Toxoplasma gondii seroprevalence in Mali. J Parasitol 99:371-4
Klinger, Christen M; Nisbet, R Ellen; Ouologuem, Dinkorma T et al. (2013) Cryptic organelle homology in apicomplexan parasites: insights from evolutionary cell biology. Curr Opin Microbiol 16:424-31
Hall, Aisling O'Hara; Beiting, Daniel P; Tato, Cristina et al. (2012) The cytokines interleukin 27 and interferon-? promote distinct Treg cell populations required to limit infection-induced pathology. Immunity 37:511-23
Pszenny, Viviana; Davis, Paul H; Zhou, Xing W et al. (2012) Targeted disruption of Toxoplasma gondii serine protease inhibitor 1 increases bradyzoite cyst formation in vitro and parasite tissue burden in mice. Infect Immun 80:1156-65
Jammallo, Lauren; Eidell, Keith; Davis, Paul H et al. (2011) An insertional trap for conditional gene expression in Toxoplasma gondii: identification of TAF250 as an essential gene. Mol Biochem Parasitol 175:133-43
Gregg, Beth; Dzierszinski, Florence; Tait, Elia et al. (2011) Subcellular antigen location influences T-cell activation during acute infection with Toxoplasma gondii. PLoS One 6:e22936

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