Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AR011949-29
Application #
2078286
Study Section
Special Emphasis Panel (NSS)
Project Start
1977-09-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
29
Fiscal Year
1996
Total Cost
Indirect Cost
Name
New York University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10016
Pillinger, M H; Capodici, C; Rosenthal, P et al. (1998) Modes of action of aspirin-like drugs: salicylates inhibit erk activation and integrin-dependent neutrophil adhesion. Proc Natl Acad Sci U S A 95:14540-5
Capodici, C; Pillinger, M H; Han, G et al. (1998) Integrin-dependent homotypic adhesion of neutrophils. Arachidonic acid activates Raf-1/Mek/Erk via a 5-lipoxygenase- dependent pathway. J Clin Invest 102:165-75
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Pillinger, M H; Capodici, C; Han, G et al. (1997) Inflammation and anti-inflammation: gating of cell/cell adhesion at the level of mitogen-activated protein kinases. Ann N Y Acad Sci 832:1-12
Wisniewski, H G; Hua, J C; Poppers, D M et al. (1996) TNF/IL-1-inducible protein TSG-6 potentiates plasmin inhibition by inter-alpha-inhibitor and exerts a strong anti-inflammatory effect in vivo. J Immunol 156:1609-15
Wisniewski, H G; Naime, D; Hua, J C et al. (1996) TSG-6, a glycoprotein associated with arthritis, and its ligand hyaluronan exert opposite effects in a murine model of inflammation. Pflugers Arch 431:R225-6
Revan, S; Montesinos, M C; Naime, D et al. (1996) Adenosine A2 receptor occupancy regulates stimulated neutrophil function via activation of a serine/threonine protein phosphatase. J Biol Chem 271:17114-8
Gadangi, P; Longaker, M; Naime, D et al. (1996) The anti-inflammatory mechanism of sulfasalazine is related to adenosine release at inflamed sites. J Immunol 156:1937-41
Pillinger, M H; Feoktistov, A S; Capodici, C et al. (1996) Mitogen-activated protein kinase in neutrophils and enucleate neutrophil cytoplasts: evidence for regulation of cell-cell adhesion. J Biol Chem 271:12049-56

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