Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AR018880-20
Application #
2078402
Study Section
Special Emphasis Panel (NSS)
Project Start
1976-06-20
Project End
1998-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
20
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Boston University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118
Lucero, H A; Kagan, H M (2006) Lysyl oxidase: an oxidative enzyme and effector of cell function. Cell Mol Life Sci 63:2304-16
Kagan, Herbert M; Li, Wande (2003) Lysyl oxidase: properties, specificity, and biological roles inside and outside of the cell. J Cell Biochem 88:660-72
Nellaiappan, K; Kagan, H M (1999) Proteins secreted by vascular smooth muscle cells as substrates of lysyl oxidase. Connect Tissue Res 40:123-9
Nagan, N; Callery, P S; Kagan, H M (1998) Aminoalkylaziridines as substrates and inhibitors of lysyl oxidase: specific inactivation of the enzyme by N-(5-aminopentyl)aziridine. Front Biosci 3:A23-6
Smith-Mungo, L I; Kagan, H M (1998) Lysyl oxidase: properties, regulation and multiple functions in biology. Matrix Biol 16:387-98
Li, W; Nellaiappan, K; Strassmaier, T et al. (1997) Localization and activity of lysyl oxidase within nuclei of fibrogenic cells. Proc Natl Acad Sci U S A 94:12817-22
Gacheru, S N; Thomas, K M; Murray, S A et al. (1997) Transcriptional and post-transcriptional control of lysyl oxidase expression in vascular smooth muscle cells: effects of TGF-beta 1 and serum deprivation. J Cell Biochem 65:395-407
Liu, G; Nellaiappan, K; Kagan, H M (1997) Irreversible inhibition of lysyl oxidase by homocysteine thiolactone and its selenium and oxygen analogues. Implications for homocystinuria. J Biol Chem 272:32370-7
Lazarus, H M; Cruikshank, W W; Narasimhan, N et al. (1995) Induction of human monocyte motility by lysyl oxidase. Matrix Biol 14:727-31
Kagan, H M; Reddy, V B; Narasimhan, N et al. (1995) Catalytic properties and structural components of lysyl oxidase. Ciba Found Symp 192:100-15;discussion 115-21

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