Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AR021707-16
Application #
2078520
Study Section
Orthopedics and Musculoskeletal Study Section (ORTH)
Project Start
1981-04-01
Project End
1997-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
16
Fiscal Year
1996
Total Cost
Indirect Cost
Name
St. Francis Hospital and Medical Center
Department
Type
DUNS #
City
Hartford
State
CT
Country
United States
Zip Code
06105
Zanotti, Stefano; Kalajzic, Ivo; Aguila, Hector Leonardo et al. (2014) Sex and genetic factors determine osteoblastic differentiation potential of murine bone marrow stromal cells. PLoS One 9:e86757
Canalis, Ernesto; Zanotti, Stefano; Smerdel-Ramoya, Anna (2014) Connective tissue growth factor is a target of notch signaling in cells of the osteoblastic lineage. Bone 64:273-80
Canalis, Ernesto (2013) Wnt signalling in osteoporosis: mechanisms and novel therapeutic approaches. Nat Rev Endocrinol 9:575-83
Zanotti, Stefano; Canalis, Ernesto (2012) Nemo-like kinase inhibits osteoblastogenesis by suppressing bone morphogenetic protein and WNT canonical signaling. J Cell Biochem 113:449-56
Canalis, Ernesto; Brunet, Lisa J; Parker, Kristen et al. (2012) Conditional inactivation of noggin in the postnatal skeleton causes osteopenia. Endocrinology 153:1616-26
Canalis, Ernesto; Parker, Kristen; Zanotti, Stefano (2012) Gremlin1 is required for skeletal development and postnatal skeletal homeostasis. J Cell Physiol 227:269-77
Beamer, Wesley G; Shultz, Kathryn L; Coombs 3rd, Harold F et al. (2011) BMD regulation on mouse distal chromosome 1, candidate genes, and response to ovariectomy or dietary fat. J Bone Miner Res 26:88-99
Myers, Michelle; Tripurani, Swamy K; Middlebrook, Brooke et al. (2011) Loss of gremlin delays primordial follicle assembly but does not affect female fertility in mice. Biol Reprod 85:1175-82
Smerdel-Ramoya, Anna; Zanotti, Stefano; Canalis, Ernesto (2011) Nephroblastoma overexpressed (Nov) induces gremlin in ST-2 stromal cell lines by post-transcriptional mechanisms. J Cell Biochem 112:715-22
Canalis, Ernesto; Zanotti, Stefano; Beamer, Wesley G et al. (2010) Connective tissue growth factor is required for skeletal development and postnatal skeletal homeostasis in male mice. Endocrinology 151:3490-501

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