Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AR027029-16
Application #
2078602
Study Section
Special Emphasis Panel (NSS)
Project Start
1980-05-01
Project End
1997-04-30
Budget Start
1995-05-01
Budget End
1997-04-30
Support Year
16
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Price, P A; Faus, S A; Williamson, M K (1998) Warfarin causes rapid calcification of the elastic lamellae in rat arteries and heart valves. Arterioscler Thromb Vasc Biol 18:1400-7
Benton, M E; Price, P A; Suttie, J W (1995) Multi-site-specificity of the vitamin K-dependent carboxylase: in vitro carboxylation of des-gamma-carboxylated bone Gla protein and Des-gamma-carboxylated pro bone Gla protein. Biochemistry 34:9541-51
Cancela, M L; Williamson, M K; Price, P A (1995) Amino-acid sequence of bone Gla protein from the African clawed toad Xenopus laevis and the fish Sparus aurata. Int J Pept Protein Res 46:419-23
Cairns, J R; Price, P A (1994) Direct demonstration that the vitamin K-dependent bone Gla protein is incompletely gamma-carboxylated in humans. J Bone Miner Res 9:1989-97
Johansen, J S; Jensen, H S; Price, P A (1993) A new biochemical marker for joint injury. Analysis of YKL-40 in serum and synovial fluid. Br J Rheumatol 32:949-55
Price, P A; Williamson, M K (1993) Substrate recognition by the vitamin K-dependent gamma-glutamyl carboxylase: identification of a sequence homology between the carboxylase and the carboxylase recognition site in the substrate. Protein Sci 2:1987-8
Johansen, J S; Williamson, M K; Rice, J S et al. (1992) Identification of proteins secreted by human osteoblastic cells in culture. J Bone Miner Res 7:501-12
Gorter de Vries, I; Wisse, E; Williamson, M K et al. (1991) Effect of warfarin on early rat tooth development. Calcif Tissue Int 49:355-8
Cairns, J R; Williamson, M K; Price, P A (1991) Direct identification of gamma-carboxyglutamic acid in the sequencing of vitamin K-dependent proteins. Anal Biochem 199:93-7