Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AR035689-12
Application #
2079098
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1985-09-23
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
Koch, M; Murrell, J R; Hunter, D D et al. (2000) A novel member of the netrin family, beta-netrin, shares homology with the beta chain of laminin: identification, expression, and functional characterization. J Cell Biol 151:221-34
Amano, S; Scott, I C; Takahara, K et al. (2000) Bone morphogenetic protein 1 is an extracellular processing enzyme of the laminin 5 gamma 2 chain. J Biol Chem 275:22728-35
Koch, M; Olson, P F; Albus, A et al. (1999) Characterization and expression of the laminin gamma3 chain: a novel, non-basement membrane-associated, laminin chain. J Cell Biol 145:605-18
Champliaud, M F; Burgeson, R E; Jin, W et al. (1998) cDNA cloning and characterization of sciellin, a LIM domain protein of the keratinocyte cornified envelope. J Biol Chem 273:31547-54
Cserhalmi-Friedman, P B; Baden, H; Burgeson, R E et al. (1998) Molecular basis of non-lethal junctional epidermolysis bullosa: identification of a 38 basepair insertion and a splice site mutation in exon 14 of the LAMB3 gene. Exp Dermatol 7:105-11
Wewer, U M; Thornell, L E; Loechel, F et al. (1997) Extrasynaptic location of laminin beta 2 chain in developing and adult human skeletal muscle. Am J Pathol 151:621-31
Gerecke, D R; Olson, P F; Koch, M et al. (1997) Complete primary structure of two splice variants of collagen XII, and assignment of alpha 1(XII) collagen (COL12A1), alpha 1(IX) collagen (COL9A1), and alpha 1(XIX) collagen (COL19A1) to human chromosome 6q12-q13. Genomics 41:236-42
Rousselle, P; Keene, D R; Ruggiero, F et al. (1997) Laminin 5 binds the NC-1 domain of type VII collagen. J Cell Biol 138:719-28
Champliaud, M F; Lunstrum, G P; Rousselle, P et al. (1996) Human amnion contains a novel laminin variant, laminin 7, which like laminin 6, covalently associates with laminin 5 to promote stable epithelial-stromal attachment. J Cell Biol 132:1189-98
Marinkovich, M P; Taylor, T B; Keene, D R et al. (1996) LAD-1, the linear IgA bullous dermatosis autoantigen, is a novel 120-kDa anchoring filament protein synthesized by epidermal cells. J Invest Dermatol 106:734-8

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