Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37CA030276-15
Application #
2088057
Study Section
Visual Sciences C Study Section (VISC)
Project Start
1981-07-01
Project End
1999-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75390
Han, Zhiqiang; Brown, Joseph R; Niederkorn, Jerry Y (2016) Growth and Metastasis of Intraocular Tumors in Aged Mice. Invest Ophthalmol Vis Sci 57:2366-76
Sadegh, Leila; Chen, Peter W; Brown, Joseph R et al. (2015) NKT cells act through third party bone marrow-derived cells to suppress NK cell activity in the liver and exacerbate hepatic melanoma metastases. Int J Cancer 137:1085-94
Niederkorn, Jerry Y (2013) Corneal transplantation and immune privilege. Int Rev Immunol 32:57-67
Li, Haochuan; Niederkorn, Jerry Y; Sadegh, Leila et al. (2013) Epigenetic regulation of CXCR4 expression by the ocular microenvironment. Invest Ophthalmol Vis Sci 54:234-43
Yang, Wanhua; Li, Haochuan; Mayhew, Elizabeth et al. (2011) NKT cell exacerbation of liver metastases arising from melanomas transplanted into either the eyes or spleens of mice. Invest Ophthalmol Vis Sci 52:3094-102
Li, Haochuan; Yang, Wanhua; Chen, Peter W et al. (2009) Inhibition of chemokine receptor expression on uveal melanomas by CXCR4 siRNA and its effect on uveal melanoma liver metastases. Invest Ophthalmol Vis Sci 50:5522-8
Niederkorn, Jerry Y (2009) Immune escape mechanisms of intraocular tumors. Prog Retin Eye Res 28:329-47
Yang, Wanhua; Li, Haochuan; Chen, Peter W et al. (2009) PD-L1 expression on human ocular cells and its possible role in regulating immune-mediated ocular inflammation. Invest Ophthalmol Vis Sci 50:273-80
Li, Haochuan; Alizadeh, Hassan; Niederkorn, Jerry Y (2008) Differential expression of chemokine receptors on uveal melanoma cells and their metastases. Invest Ophthalmol Vis Sci 49:636-43
Yang, Wanhua; Chen, Peter W; Li, Haochuan et al. (2008) PD-L1: PD-1 interaction contributes to the functional suppression of T-cell responses to human uveal melanoma cells in vitro. Invest Ophthalmol Vis Sci 49:2518-25

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