Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37CA032436-15
Application #
2088339
Study Section
Special Emphasis Panel (NSS)
Project Start
1982-05-01
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Chicago
Department
Genetics
Type
Schools of Medicine
DUNS #
225410919
City
Chicago
State
IL
Country
United States
Zip Code
60637
Strauss, Bernard; Kelly, Kemba; Ekiert, Damian (2005) Cytochrome oxidase deficiency protects Escherichia coli from cell death but not from filamentation due to thymine deficiency or DNA polymerase inactivation. J Bacteriol 187:2827-35
Strauss, Bernard S (2002) The ""A"" rule revisited: polymerases as determinants of mutational specificity. DNA Repair (Amst) 1:125-35
Strauss, B S; Roberts, R; Francis, L et al. (2000) Role of the dinB gene product in spontaneous mutation in Escherichia coli with an impaired replicative polymerase. J Bacteriol 182:6742-50
Strauss, B S (2000) Role in tumorigenesis of silent mutations in the TP53 gene. Mutat Res 457:93-104
Strauss, B S (2000) The stability of the genome and the genetic instability of tumors. Perspect Biol Med 43:286-300
Strauss, B S (1999) Frameshift mutation, microsatellites and mismatch repair. Mutat Res 437:195-203
Sagher, D; Hsu, A; Strauss, B (1999) Stabilization of the intermediate in frameshift mutation. Mutat Res 423:73-7
Strauss, B S (1998) Hypermutability in carcinogenesis. Genetics 148:1619-26
Strauss, B S (1997) Silent and multiple mutations in p53 and the question of the hypermutability of tumors. Carcinogenesis 18:1445-52
Strauss, B S; Sagher, D; Acharya, S (1997) Role of proofreading and mismatch repair in maintaining the stability of nucleotide repeats in DNA. Nucleic Acids Res 25:806-13

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