Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37CA034610-20
Application #
6512434
Study Section
Special Emphasis Panel (NSS)
Program Officer
Freeman, Colette S
Project Start
1983-05-01
Project End
2005-04-30
Budget Start
2002-05-01
Budget End
2003-04-30
Support Year
20
Fiscal Year
2002
Total Cost
$348,794
Indirect Cost
Name
Sloan-Kettering Institute for Cancer Research
Department
Type
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10065
Macias, Maria J; Martin-Malpartida, Pau; Massagué, Joan (2015) Structural determinants of Smad function in TGF-? signaling. Trends Biochem Sci 40:296-308
Calon, Alexandre; Espinet, Elisa; Palomo-Ponce, Sergio et al. (2014) Immunostaining Protocol: P-Stat3 (Xenograft and Mice). Bio Protoc 4:
Oskarsson, Thordur; Batlle, Eduard; Massagué, Joan (2014) Metastatic stem cells: sources, niches, and vital pathways. Cell Stem Cell 14:306-21
Vanharanta, Sakari; Massagué, Joan (2013) Origins of metastatic traits. Cancer Cell 24:410-21
Stankic, Marko; Pavlovic, Svetlana; Chin, Yvette et al. (2013) TGF-?-Id1 signaling opposes Twist1 and promotes metastatic colonization via a mesenchymal-to-epithelial transition. Cell Rep 5:1228-42
Hynes, Nancy E; Ingham, Philip W; Lim, Wendell A et al. (2013) Signalling change: signal transduction through the decades. Nat Rev Mol Cell Biol 14:393-8
Vanharanta, Sakari; Massagué, Joan (2013) Hypoxia signaling--license to metastasize. Cancer Discov 3:1103-4
Acharyya, Swarnali; Oskarsson, Thordur; Vanharanta, Sakari et al. (2012) A CXCL1 paracrine network links cancer chemoresistance and metastasis. Cell 150:165-78
Aragón, Eric; Goerner, Nina; Xi, Qiaoran et al. (2012) Structural basis for the versatile interactions of Smad7 with regulator WW domains in TGF-? Pathways. Structure 20:1726-36
Calon, Alexandre; Espinet, Elisa; Palomo-Ponce, Sergio et al. (2012) Dependency of colorectal cancer on a TGF-?-driven program in stromal cells for metastasis initiation. Cancer Cell 22:571-84

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