Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37CA038597-11
Application #
2089599
Study Section
Special Emphasis Panel (NSS)
Project Start
1985-01-01
Project End
1996-12-31
Budget Start
1995-01-01
Budget End
1996-12-31
Support Year
11
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Poon, B; Chen, I S (1998) Identification of a domain within the human T-cell leukemia virus type 2 envelope required for syncytium induction and replication. J Virol 72:1959-66
Li, Q X; Camerini, D; Xie, Y et al. (1996) Syncytium formation by recombinant HTLV-II envelope glycoprotein. Virology 218:279-84
Feuer, G; Fraser, J K; Zack, J A et al. (1996) Human T-cell leukemia virus infection of human hematopoietic progenitor cells: maintenance of virus infection during differentiation in vitro and in vivo. J Virol 70:4038-44
Stewart, S A; Feuer, G; Jewett, A et al. (1996) HTLV-1 gene expression in adult T-cell leukemia cells elicits an NK cell response in vitro and correlates with cell rejection in SCID mice. Virology 226:167-75
Cockerell, G L; Rovnak, J; Green, P L et al. (1996) A deletion in the proximal untranslated pX region of human T-cell leukemia virus type II decreases viral replication but not infectivity in vivo. Blood 87:1030-5
Green, P L; Yip, M T; Xie, Y et al. (1992) Phosphorylation regulates RNA binding by the human T-cell leukemia virus Rex protein. J Virol 66:4325-30
Arrigo, S J; Chen, I S (1991) Rev is necessary for translation but not cytoplasmic accumulation of HIV-1 vif, vpr, and env/vpu 2 RNAs. Genes Dev 5:808-19
Yip, M T; Dynan, W S; Green, P L et al. (1991) Human T-cell leukemia virus (HTLV) type II Rex protein binds specifically to RNA sequences of the HTLV long terminal repeat but poorly to the human immunodeficiency virus type 1 Rev-responsive element. J Virol 65:2261-72
Black, A C; Chen, I S; Arrigo, S et al. (1991) Regulation of HTLV-II gene expression by Rex involves positive and negative cis-acting elements in the 5'long terminal repeat. Virology 181:433-44
Green, P L; Xie, Y M; Chen, I S (1991) The Rex proteins of human T-cell leukemia virus type II differ by serine phosphorylation. J Virol 65:546-50

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