Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37CA039207-12
Application #
2089755
Study Section
Special Emphasis Panel (NSS)
Project Start
1991-01-01
Project End
1999-12-31
Budget Start
1996-03-20
Budget End
1996-12-31
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Wu, Yi-Mi; Robinson, Dan R; Kung, Hsing-Jien (2004) Signal pathways in up-regulation of chemokines by tyrosine kinase MER/NYK in prostate cancer cells. Cancer Res 64:7311-20
Lee, Li-Fen; Louie, Maggie C; Desai, Sonal J et al. (2004) Interleukin-8 confers androgen-independent growth and migration of LNCaP: differential effects of tyrosine kinases Src and FAK. Oncogene 23:2197-205
Chen, Kai-Yun; Huang, Li-Ming; Kung, Hsing-Jien et al. (2004) The role of tyrosine kinase Etk/Bmx in EGF-induced apoptosis of MDA-MB-468 breast cancer cells. Oncogene 23:1854-62
Yustein, Jason T; Xia, Liang; Kahlenburg, J Michelle et al. (2003) Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38. Oncogene 22:6129-41
Xia, Liang; Robinson, Dan; Ma, Ai-Hong et al. (2002) Identification of human male germ cell-associated kinase, a kinase transcriptionally activated by androgen in prostate cancer cells. J Biol Chem 277:35422-33
Tepper, Clifford G; Boucher, David L; Ryan, Philip E et al. (2002) Characterization of a novel androgen receptor mutation in a relapsed CWR22 prostate cancer xenograft and cell line. Cancer Res 62:6606-14
Lee, L F; Guan, J; Qiu, Y et al. (2001) Neuropeptide-induced androgen independence in prostate cancer cells: roles of nonreceptor tyrosine kinases Etk/Bmx, Src, and focal adhesion kinase. Mol Cell Biol 21:8385-97
Yustein, J T; Li, D; Robinson, D et al. (2000) KFC, a Ste20-like kinase with mitogenic potential and capability to activate the SAPK/JNK pathway. Oncogene 19:710-8
Jui, H Y; Tseng, R J; Wen, X et al. (2000) Protein-tyrosine phosphatase D1, a potential regulator and effector for Tec family kinases. J Biol Chem 275:41124-32
Tsai, Y T; Su, Y H; Fang, S S et al. (2000) Etk, a Btk family tyrosine kinase, mediates cellular transformation by linking Src to STAT3 activation. Mol Cell Biol 20:2043-54

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