Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37CA046613-09
Application #
2092248
Study Section
Experimental Virology Study Section (EVR)
Project Start
1988-03-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Levy, Alon M; Gilad, Oren; Xia, Liang et al. (2005) Marek's disease virus Meq transforms chicken cells via the v-Jun transcriptional cascade: a converging transforming pathway for avian oncoviruses. Proc Natl Acad Sci U S A 102:14831-6
Cui, Xiaoping; Lee, Lucy F; Reed, Willie M et al. (2004) Marek's disease virus-encoded vIL-8 gene is involved in early cytolytic infection but dispensable for establishment of latency. J Virol 78:4753-60
Yustein, Jason T; Xia, Liang; Kahlenburg, J Michelle et al. (2003) Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38. Oncogene 22:6129-41
Izumiya, Yoshihiro; Lin, Su-Fang; Ellison, Thomas J et al. (2003) Cell cycle regulation by Kaposi's sarcoma-associated herpesvirus K-bZIP: direct interaction with cyclin-CDK2 and induction of G1 growth arrest. J Virol 77:9652-61
Kung, H J; Kamil, J; Witter, R et al. (2001) Retroviral insertion into herpesviruses: discovery and implications. Dev Biol (Basel) 106:223-8; discussion 228-9, 253-63
Parcells, M S; Lin, S F; Dienglewicz, R L et al. (2001) Marek's disease virus (MDV) encodes an interleukin-8 homolog (vIL-8): characterization of the vIL-8 protein and a vIL-8 deletion mutant MDV. J Virol 75:5159-73
Yustein, J T; Li, D; Robinson, D et al. (2000) KFC, a Ste20-like kinase with mitogenic potential and capability to activate the SAPK/JNK pathway. Oncogene 19:710-8
Liu, J L; Kung, H J (2000) Marek's disease herpesvirus transforming protein MEQ: a c-Jun analogue with an alternative life style. Virus Genes 21:51-64
Lee, L F; Wu, P; Sui, D et al. (2000) The complete unique long sequence and the overall genomic organization of the GA strain of Marek's disease virus. Proc Natl Acad Sci U S A 97:6091-6
Lin, S F; Robinson, D R; Miller, G et al. (1999) Kaposi's sarcoma-associated herpesvirus encodes a bZIP protein with homology to BZLF1 of Epstein-Barr virus. J Virol 73:1909-17

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