Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
7R37DA002643-16
Application #
2116628
Study Section
Special Emphasis Panel (SRCD (10))
Project Start
1992-08-01
Project End
1997-06-30
Budget Start
1995-10-01
Budget End
1996-06-30
Support Year
16
Fiscal Year
1995
Total Cost
Indirect Cost
Name
California Pacific Medical Center Research Institute
Department
Type
DUNS #
City
San Francisco
State
CA
Country
United States
Zip Code
94107
Riba, Pal; Ben, Yong; Nguyen, Thi M-D et al. (2002) [Dmt(1)]DALDA is highly selective and potent at mu opioid receptors, but is not cross-tolerant with systemic morphine. Curr Med Chem 9:31-9
Riba, Pal; Ben, Yong; Smith, Andrew P et al. (2002) Morphine tolerance in spinal cord is due to interaction between mu- and delta-receptors. J Pharmacol Exp Ther 300:265-72
Gant, T M; Riba, P; Lee, N M (2001) Morphine tolerance in mice is independent of polymorphisms in opioid receptor sequences. Brain Res Bull 55:59-63
He, L; Lee, N M (1998) Delta opioid receptor enhancement of mu opioid receptor-induced antinociception in spinal cord. J Pharmacol Exp Ther 285:1181-6
He, L; Lee, N M (1997) DynorphinA-(2-17) restores spinal/supraspinal morphine synergy in morphine-tolerant mice. J Pharmacol Exp Ther 280:1210-4
Lee, N M (1995) Dynorphin A: a rectifying peptide. NIDA Res Monogr 147:161-9
Lane, C M; Jones, C R; Reisine, T et al. (1995) Alteration of OBCAM conformation as a result of opioid receptor expression and opioid ligand treatment. Brain Res 698:15-22
Kalyuzhny, A; Lee, N M; Elde, R (1995) An opioid binding protein is specifically down-regulated by chronic morphine treatment in dorsal root and trigeminal ganglia. Neuroscience 66:943-9
Pentel, P R; Wananukul, W; Hooke, L P et al. (1995) Effects of high intravenous doses of dynorphin A(1-13) on tail flick latency and central nervous system histology in rats. Pharmacol Biochem Behav 51:387-90
Hooke, L P; He, L; Lee, N M (1995) Dynorphin A modulates acute and chronic opioid effects. J Pharmacol Exp Ther 273:292-7

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