Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37DK014574-27
Application #
2136848
Study Section
Special Emphasis Panel (NSS)
Project Start
1975-01-01
Project End
1997-12-31
Budget Start
1996-02-27
Budget End
1996-12-31
Support Year
27
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Modan-Moses, D; Janicot, M; McLenithan, J C et al. (1998) Expression and function of insulin/insulin-like growth factor I hybrid receptors during differentiation of 3T3-L1 preadipocytes. Biochem J 333 ( Pt 3):825-31
Ezaki, O; Flores-Riveros, J R; Kaestner, K H et al. (1993) Regulated expression of an insulin-responsive glucose transporter (GLUT4) minigene in 3T3-L1 adipocytes and transgenic mice. Proc Natl Acad Sci U S A 90:3348-52
Hoffman, R D; Lane, M D (1992) Iodophenylarsine oxide and arsenical affinity chromatography: new probes for dithiol proteins. Application to tubulins and to components of the insulin receptor-glucose transporter signal transduction pathway. J Biol Chem 267:14005-11
Janicot, M; Flores-Riveros, J R; Lane, M D (1991) The insulin-like growth factor 1 (IGF-1) receptor is responsible for mediating the effects of insulin, IGF-1, and IGF-2 in Xenopus laevis oocytes. J Biol Chem 266:9382-91
Liao, K; Hoffman, R D; Lane, M D (1991) Phosphotyrosyl turnover in insulin signaling. Characterization of two membrane-bound pp15 protein tyrosine phosphatases from 3T3-L1 adipocytes. J Biol Chem 266:6544-53
Hresko, R C; Hoffman, R D; Flores-Riveros, J R et al. (1990) Insulin receptor tyrosine kinase-catalyzed phosphorylation of 422(aP2) protein. Substrate activation by long-chain fatty acid. J Biol Chem 265:21075-85
Lane, M D; Flores-Riveros, J R; Hresko, R C et al. (1990) Insulin-receptor tyrosine kinase and glucose transport. Diabetes Care 13:565-75
Kaestner, K H; Christy, R J; McLenithan, J C et al. (1989) Sequence, tissue distribution, and differential expression of mRNA for a putative insulin-responsive glucose transporter in mouse 3T3-L1 adipocytes. Proc Natl Acad Sci U S A 86:3150-4
Flores-Riveros, J R; Sibley, E; Kastelic, T et al. (1989) Substrate phosphorylation catalyzed by the insulin receptor tyrosine kinase. Kinetic correlation to autophosphorylation of specific sites in the beta subunit. J Biol Chem 264:21557-72
Janicot, M; Lane, M D (1989) Activation of glucose uptake by insulin and insulin-like growth factor I in Xenopus oocytes. Proc Natl Acad Sci U S A 86:2642-6

Showing the most recent 10 out of 14 publications