Alpha and Beta Cell Function in Human Diabetes

Gerich, John E.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Method to Extend Research in Time (MERIT) Award (R37)
• Project #: 7R37DK020411-19
• Application #: 2137459
• Study Section: Metabolism Study Section (MET)
• Project Start: 1986-12-01
• Project End: 1996-06-30
• Budget Start: 1994-04-01
• Budget End: 1996-06-30
• Support Year: 19
• Fiscal Year: 1993

Institution

• Name: University of Rochester
• Department: Internal Medicine/Medicine
• Type: Schools of Dentistry
• DUNS #: 208469486
• City: Rochester
• State: NY
• Country: United States
• Zip Code: 14627

Publications

Emerson, Peter; Van Haeften, Timon W; Pimenta, Walkyria et al. (2009) Different pathophysiology of impaired glucose tolerance in first-degree relatives of individuals with type 2 diabetes mellitus. Metabolism 58:602-7

Woerle, Hans J; Albrecht, Max; Linke, Rainer et al. (2008) Impaired hyperglycemia-induced delay in gastric emptying in patients with type 1 diabetes deficient for islet amyloid polypeptide. Diabetes Care 31:2325-31

Woerle, H-J; Albrecht, M; Linke, R et al. (2008) Importance of changes in gastric emptying for postprandial plasma glucose fluxes in healthy humans. Am J Physiol Endocrinol Metab 294:E103-9

Szoke, Ervin; Shrayyef, Muhammad Z; Messing, Susan et al. (2008) Effect of aging on glucose homeostasis: accelerated deterioration of beta-cell function in individuals with impaired glucose tolerance. Diabetes Care 31:539-43

Schwarz, S L; Gerich, J E; Marcellari, A et al. (2008) Nateglinide, alone or in combination with metformin, is effective and well tolerated in treatment-naive elderly patients with type 2 diabetes. Diabetes Obes Metab 10:652-60

Woerle, Hans J; Neumann, Christoph; Zschau, Silvia et al. (2007) Impact of fasting and postprandial glycemia on overall glycemic control in type 2 diabetes Importance of postprandial glycemia to achieve target HbA1c levels. Diabetes Res Clin Pract 77:280-5

Gerich, John E (2006) Postprandial hyperglycemia and cardiovascular disease. Endocr Pract 12 Suppl 1:47-51

Woerle, Hans J; Szoke, Ervin; Meyer, Christian et al. (2006) Mechanisms for abnormal postprandial glucose metabolism in type 2 diabetes. Am J Physiol Endocrinol Metab 290:E67-E77

Israelian, Zarmen; Szoke, Ervin; Woerle, Juergen et al. (2006) Multiple defects in counterregulation of hypoglycemia in modestly advanced type 2 diabetes mellitus. Metabolism 55:593-8

Meyer, Christian; Pimenta, Walkyria; Woerle, Hans J et al. (2006) Different mechanisms for impaired fasting glucose and impaired postprandial glucose tolerance in humans. Diabetes Care 29:1909-14