Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37DK021860-19
Application #
2137628
Study Section
Special Emphasis Panel (NSS)
Project Start
1978-07-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
19
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Albert Einstein College of Medicine
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
009095365
City
Bronx
State
NY
Country
United States
Zip Code
10461
Radulescu, Andreea E; Shields, Dennis (2012) Clathrin is required for postmitotic Golgi reassembly. FASEB J 26:129-36
Radulescu, Andreea E; Mukherjee, Shaeri; Shields, Dennis (2011) The Golgi protein p115 associates with gamma-tubulin and plays a role in Golgi structure and mitosis progression. J Biol Chem 286:21915-26
How, Poh Choo; Shields, Dennis (2011) Tethering function of the caspase cleavage fragment of Golgi protein p115 promotes apoptosis via a p53-dependent pathway. J Biol Chem 286:8565-76
Riebeling, Christian; Morris, Andrew J; Shields, Dennis (2009) Phospholipase D in the Golgi apparatus. Biochim Biophys Acta 1791:876-80
Mukherjee, Shaeri; Shields, Dennis (2009) Nuclear import is required for the pro-apoptotic function of the Golgi protein p115. J Biol Chem 284:1709-17
Mukherjee, Shaeri; Chiu, Raymond; Leung, Som-Ming et al. (2007) Fragmentation of the Golgi apparatus: an early apoptotic event independent of the cytoskeleton. Traffic 8:369-78
Radulescu, Andreea E; Siddhanta, Anirban; Shields, Dennis (2007) A role for clathrin in reassembly of the Golgi apparatus. Mol Biol Cell 18:94-105
Cai, Dongming; Zhong, Minghao; Wang, Runsheng et al. (2006) Phospholipase D1 corrects impaired betaAPP trafficking and neurite outgrowth in familial Alzheimer's disease-linked presenilin-1 mutant neurons. Proc Natl Acad Sci U S A 103:1936-40
Freyberg, Zachary; Siddhanta, Anirban; Shields, Dennis (2003) ""Slip, sliding away"": phospholipase D and the Golgi apparatus. Trends Cell Biol 13:540-6
Siddhanta, Anirban; Radulescu, Andreea; Stankewich, Michael C et al. (2003) Fragmentation of the Golgi apparatus. A role for beta III spectrin and synthesis of phosphatidylinositol 4,5-bisphosphate. J Biol Chem 278:1957-65

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