Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37DK037139-16
Application #
6517105
Study Section
Special Emphasis Panel (NSS)
Program Officer
Wilder, Elizabeth L
Project Start
1987-07-01
Project End
2004-06-30
Budget Start
2002-07-01
Budget End
2003-06-30
Support Year
16
Fiscal Year
2002
Total Cost
$481,470
Indirect Cost
Name
University of Texas Health Science Center San Antonio
Department
Pathology
Type
Other Domestic Higher Education
DUNS #
800772162
City
San Antonio
State
TX
Country
United States
Zip Code
78229
Venkatachalam, Manjeri A; Weinberg, Joel M (2017) Pericytes Preserve Capillary Integrity to Prevent Kidney Hypoxia. J Am Soc Nephrol 28:717-719
Singha, P K; Pandeswara, S; Venkatachalam, M A et al. (2013) Manumycin A inhibits triple-negative breast cancer growth through LC3-mediated cytoplasmic vacuolation death. Cell Death Dis 4:e457
Lan, Rongpei; Geng, Hui; Polichnowski, Aaron J et al. (2012) PTEN loss defines a TGF-?-induced tubule phenotype of failed differentiation and JNK signaling during renal fibrosis. Am J Physiol Renal Physiol 302:F1210-23
Geng, Hui; Lan, Rongpei; Singha, Prajjal K et al. (2012) Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and G?q-mediated Rho and ?v?6 integrin-dependent activation of TGF-?. Am J Pathol 181:1236-49
Venkatachalam, Manjeri A; Griffin, Karen A; Lan, Rongpei et al. (2010) Acute kidney injury: a springboard for progression in chronic kidney disease. Am J Physiol Renal Physiol 298:F1078-94
Kar, Rekha; Mishra, Nandita; Singha, Prajjal K et al. (2010) Mitochondrial remodeling following fission inhibition by 15d-PGJ2 involves molecular changes in mitochondrial fusion protein OPA1. Biochem Biophys Res Commun 399:548-54
Zitta, Karina; Brandt, Berenice; Wuensch, Annegret et al. (2010) Interleukin-1beta regulates cell proliferation and activity of extracellular matrix remodelling enzymes in cultured primary pig heart cells. Biochem Biophys Res Commun 399:542-7
Singha, Prajjal K; Yeh, I-Tien; Venkatachalam, Manjeri A et al. (2010) Transforming growth factor-beta (TGF-beta)-inducible gene TMEPAI converts TGF-beta from a tumor suppressor to a tumor promoter in breast cancer. Cancer Res 70:6377-83
Mishra, Nandita; Kar, Rekha; Singha, Prajjal K et al. (2010) Inhibition of mitochondrial division through covalent modification of Drp1 protein by 15 deoxy-Delta(12,14)-prostaglandin J2. Biochem Biophys Res Commun 395:17-24
Lan, Rongpei; Geng, Hui; Hwang, Yoon et al. (2010) A novel wounding device suitable for quantitative biochemical analysis of wound healing and regeneration of cultured epithelium. Wound Repair Regen 18:159-67

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