Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37ES004391-10
Application #
2153677
Study Section
Special Emphasis Panel (NSS)
Project Start
1987-07-01
Project End
1997-08-31
Budget Start
1996-07-01
Budget End
1997-08-31
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Rochester
Department
Physiology
Type
Schools of Dentistry
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627
Maines, Mahin D (2002) Heme oxygenase 1 transgenic mice as a model to study neuroprotection. Methods Enzymol 353:374-88
Ahmad, Zulfiqar; Salim, Mohammad; Maines, Mahin D (2002) Human biliverdin reductase is a leucine zipper-like DNA-binding protein and functions in transcriptional activation of heme oxygenase-1 by oxidative stress. J Biol Chem 277:9226-32
Salim, M; Brown-Kipphut, B A; Maines, M D (2001) Human biliverdin reductase is autophosphorylated, and phosphorylation is required for bilirubin formation. J Biol Chem 276:10929-34
Panahian, N; Maines, M D (2001) Site of injury-directed induction of heme oxygenase-1 and -2 in experimental spinal cord injury: differential functions in neuronal defense mechanisms? J Neurochem 76:539-54
Maines, M D; Panahian, N (2001) The heme oxygenase system and cellular defense mechanisms. Do HO-1 and HO-2 have different functions? Adv Exp Med Biol 502:249-72
Maines, M D; Ewing, J F; Huang, T J et al. (2001) Nuclear localization of biliverdin reductase in the rat kidney: response to nephrotoxins that induce heme oxygenase-1. J Pharmacol Exp Ther 296:1091-7
Huang, T J; McCoubrey Jr, W K; Maines, M D (2001) Heme oxygenase-2 interaction with metalloporphyrins: function of heme regulatory motifs. Antioxid Redox Signal 3:685-96
Liu, N; Wang, X; McCoubrey, W K et al. (2000) Developmentally regulated expression of two transcripts for heme oxygenase-2 with a first exon unique to rat testis: control by corticosterone of the oxygenase protein expression. Gene 241:175-83
Chen, K; Gunter, K; Maines, M D (2000) Neurons overexpressing heme oxygenase-1 resist oxidative stress-mediated cell death. J Neurochem 75:304-13
Ding, Y; McCoubrey Jr, W K; Maines, M D (1999) Interaction of heme oxygenase-2 with nitric oxide donors. Is the oxygenase an intracellular 'sink' for NO? Eur J Biochem 264:854-61

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