Work will be conducted on three separate aspects of human color vision. Chromatic discrimination will be studied from an analytical and theoretical viewpoint, with the goal of predicting, on the basis of physical measurements, the percentage of the population who will accept a given pair of reflecting samples as a color match. Using reflecting samples that cover the entire domain of object-color perception, categorical color perception will be studied using a color naming procedure to determine the eleven basic focal colors as seen under a particular illuminant. The procedure will be extended to study color constancy, color rendering, and the limitations on naming of surface colors imposed by color-deficient vision. The relation between color-defective vision and glaucoma is the third area of study. An automated perimeter will be modified to permit the determination of shortwave-sensitive (blue) cone thresholds across the visual field in normals, glaucoma suspects, and glaucoma patients. The test may reveal early evidence of field defects in glaucoma suspects and thereby support a decision to begin treatment at a stage where visual loss is otherwise negligible; also it may prove more sensitive than current white-light procedures for monitoring the course of the disease.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37EY001541-16
Application #
3483907
Study Section
Visual Sciences B Study Section (VISB)
Project Start
1976-08-01
Project End
1991-07-31
Budget Start
1989-08-01
Budget End
1990-07-31
Support Year
16
Fiscal Year
1989
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Type
Schools of Arts and Sciences
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Sample, P A; Esterson, F D; Weinreb, R N et al. (1988) The aging lens: in vivo assessment of light absorption in 84 human eyes. Invest Ophthalmol Vis Sci 29:1306-11