Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37GM019416-25
Application #
2173451
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Project Start
1977-05-01
Project End
1997-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
25
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Feinauer, Christoph; Szurmant, Hendrik; Weigt, Martin et al. (2016) Inter-Protein Sequence Co-Evolution Predicts Known Physical Interactions in Bacterial Ribosomes and the Trp Operon. PLoS One 11:e0149166
Wu, R; Gu, M; Wilton, R et al. (2013) Insight into the sporulation phosphorelay: crystal structure of the sensor domain of Bacillus subtilis histidine kinase, KinD. Protein Sci 22:564-76
Pokkuluri, P Raj; Dwulit-Smith, Jeff; Duke, Norma E et al. (2013) Analysis of periplasmic sensor domains from Anaeromyxobacter dehalogenans 2CP-C: structure of one sensor domain from a histidine kinase and another from a chemotaxis protein. Microbiologyopen 2:766-77
Perego, Marta (2013) Forty years in the making: understanding the molecular mechanism of peptide regulation in bacterial development. PLoS Biol 11:e1001516
Szurmant, Hendrik; Hoch, James A (2013) Statistical analyses of protein sequence alignments identify structures and mechanisms in signal activation of sensor histidine kinases. Mol Microbiol 87:707-12
Bobay, Benjamin G; Hoch, James A; Cavanagh, John (2012) Dynamics and activation in response regulators: the ?4-?4 loop. Biomol Concepts 3:175-182
Diaz, Alejandra R; Core, Leighton J; Jiang, Min et al. (2012) Bacillus subtilis RapA phosphatase domain interaction with its substrate, phosphorylated Spo0F, and its inhibitor, the PhrA peptide. J Bacteriol 194:1378-88
Dago, Angel E; Schug, Alexander; Procaccini, Andrea et al. (2012) Structural basis of histidine kinase autophosphorylation deduced by integrating genomics, molecular dynamics, and mutagenesis. Proc Natl Acad Sci U S A 109:E1733-42
Baker, Kris Ann; Perego, Marta (2011) Transcription antitermination by a phosphorylated response regulator and cobalamin-dependent termination at a B?? riboswitch contribute to ethanolamine utilization in Enterococcus faecalis. J Bacteriol 193:2575-86
Chiang, Christina; Bongiorni, Cristina; Perego, Marta (2011) Glucose-dependent activation of Bacillus anthracis toxin gene expression and virulence requires the carbon catabolite protein CcpA. J Bacteriol 193:52-62

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