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de Bruyn Kops, Anne; Guthrie, Christine (2018) Identification of the Novel Nup188-brr7 Allele in a Screen for Cold-Sensitive mRNA Export Mutants in Saccharomyces cerevisiae. G3 (Bethesda) 8:2991-3003
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Nissen, Kelly E; Homer, Christina M; Ryan, Colm J et al. (2017) The histone variant H2A.Z promotes splicing of weak introns. Genes Dev 31:688-701
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Ledoux, Sarah; Guthrie, Christine (2016) Retinitis Pigmentosa Mutations in Bad Response to Refrigeration 2 (Brr2) Impair ATPase and Helicase Activity. J Biol Chem 291:11954-65
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Patrick, Kristin L; Ryan, Colm J; Xu, Jiewei et al. (2015) Genetic interaction mapping reveals a role for the SWI/SNF nucleosome remodeler in spliceosome activation in fission yeast. PLoS Genet 11:e1005074
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Blanco, Mario R; Martin, Joshua S; Kahlscheuer, Matthew L et al. (2015) Single Molecule Cluster Analysis dissects splicing pathway conformational dynamics. Nat Methods 12:1077-84
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Hadjivassiliou, Haralambos; Rosenberg, Oren S; Guthrie, Christine (2014) The crystal structure of S. cerevisiae Sad1, a catalytically inactive deubiquitinase that is broadly required for pre-mRNA splicing. RNA 20:656-69
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Ryan, Colm J; Roguev, Assen; Patrick, Kristin et al. (2012) Hierarchical modularity and the evolution of genetic interactomes across species. Mol Cell 46:691-704
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Plocik, Alex M; Guthrie, Christine (2012) Diverse forms of RPS9 splicing are part of an evolving autoregulatory circuit. PLoS Genet 8:e1002620
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Bergkessel, Megan; Whitworth, Gregg B; Guthrie, Christine (2011) Diverse environmental stresses elicit distinct responses at the level of pre-mRNA processing in yeast. RNA 17:1461-78
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Abelson, John; Blanco, Mario; Ditzler, Mark A et al. (2010) Conformational dynamics of single pre-mRNA molecules during in vitro splicing. Nat Struct Mol Biol 17:504-12
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Showing the most recent 10 out of 85 publications
