Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37GM025349-19
Application #
2174431
Study Section
Special Emphasis Panel (NSS)
Project Start
1978-09-01
Project End
2001-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
19
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Rochester
Department
Biochemistry
Type
Schools of Dentistry
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627
Ahmad, Zulfiqar; Senior, Alan E (2006) Inhibition of the ATPase activity of Escherichia coli ATP synthase by magnesium fluoride. FEBS Lett 580:517-20
Ahmad, Zulfiqar; Senior, Alan E (2005) Modulation of charge in the phosphate binding site of Escherichia coli ATP synthase. J Biol Chem 280:27981-9
Ahmad, Zulfiqar; Senior, Alan E (2005) Identification of phosphate binding residues of Escherichia coli ATP synthase. J Bioenerg Biomembr 37:437-40
Wilkens, Stephan; Borchardt, Dan; Weber, Joachim et al. (2005) Structural characterization of the interaction of the delta and alpha subunits of the Escherichia coli F1F0-ATP synthase by NMR spectroscopy. Biochemistry 44:11786-94
Ahmad, Zulfiqar; Senior, Alan E (2005) Involvement of ATP synthase residues alphaArg-376, betaArg-182, and betaLys-155 in Pi binding. FEBS Lett 579:523-8
Weber, Joachim; Senior, Alan E (2004) Fluorescent probes applied to catalytic cooperativity in ATP synthase. Methods Enzymol 380:132-52
Weber, Joachim; Wilke-Mounts, Susan; Nadanaciva, Sashi et al. (2004) Quantitative determination of direct binding of b subunit to F1 in Escherichia coli F1F0-ATP synthase. J Biol Chem 279:11253-8
Weber, Joachim; Muharemagic, Alma; Wilke-Mounts, Susan et al. (2004) Analysis of sequence determinants of F1Fo-ATP synthase in the N-terminal region of alpha subunit for binding of delta subunit. J Biol Chem 279:25673-9
Senior, Alan E; Weber, Joachim (2004) Happy motoring with ATP synthase. Nat Struct Mol Biol 11:110-2
Ahmad, Zulfiqar; Senior, Alan E (2004) Mutagenesis of residue betaArg-246 in the phosphate-binding subdomain of catalytic sites of Escherichia coli F1-ATPase. J Biol Chem 279:31505-13

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