Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37GM027875-17
Application #
2175025
Study Section
Genetics Study Section (GEN)
Project Start
1980-04-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
17
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Carnegie Institution of Washington, D.C.
Department
Type
DUNS #
072641707
City
Washington
State
DC
Country
United States
Zip Code
20005
Kotova, Elena; Jarnik, Michael; Tulin, Alexei V (2010) Uncoupling of the transactivation and transrepression functions of PARP1 protein. Proc Natl Acad Sci U S A 107:6406-11
Ji, Yingbiao; Tulin, Alexei V (2009) Poly(ADP-ribosyl)ation of heterogeneous nuclear ribonucleoproteins modulates splicing. Nucleic Acids Res 37:3501-13
Kotova, Elena; Jarnik, Michael; Tulin, Alexei V (2009) Poly (ADP-ribose) polymerase 1 is required for protein localization to Cajal body. PLoS Genet 5:e1000387
Pinnola, Aaron; Naumova, Natasha; Shah, Meera et al. (2007) Nucleosomal core histones mediate dynamic regulation of poly(ADP-ribose) polymerase 1 protein binding to chromatin and induction of its enzymatic activity. J Biol Chem 282:32511-9
Tulin, Alexei; Chinenov, Yurii; Spradling, Allan (2003) Regulation of chromatin structure and gene activity by poly(ADP-ribose) polymerases. Curr Top Dev Biol 56:55-83
Tulin, Alexei; Spradling, Allan (2003) Chromatin loosening by poly(ADP)-ribose polymerase (PARP) at Drosophila puff loci. Science 299:560-2
Tulin, Alexei; Stewart, Dianne; Spradling, Allan C (2002) The Drosophila heterochromatic gene encoding poly(ADP-ribose) polymerase (PARP) is required to modulate chromatin structure during development. Genes Dev 16:2108-19
Calvi, B R; Spradling, A C (2001) The nuclear location and chromatin organization of active chorion amplification origins. Chromosoma 110:159-72
Lilly, M A; de Cuevas, M; Spradling, A C (2000) Cyclin A associates with the fusome during germline cyst formation in the Drosophila ovary. Dev Biol 218:53-63
Dej, K J; Spradling, A C (1999) The endocycle controls nurse cell polytene chromosome structure during Drosophila oogenesis. Development 126:293-303

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