Bioinorganic Copper Coordination Chemistry - Kenneth Karlin

Abstract

Funding Agency

Agency: National Institute of Health (NIH)
Institute: National Institute of General Medical Sciences (NIGMS)
Type: Method to Extend Research in Time (MERIT) Award (R37)
Project #: 5R37GM028962-16
Application #: 2175340
Study Section: Metallobiochemistry Study Section (BMT)

Project Start: 1990-04-01
Project End: 1998-03-31
Budget Start: 1996-04-01
Budget End: 1997-03-31
Support Year: 16
Fiscal Year: 1996
Total Cost
Indirect Cost

Institution

Name: Johns Hopkins University
Department: Chemistry
Type: Schools of Arts and Sciences
DUNS #: 045911138

City: Baltimore
State: MD
Country: United States
Zip Code: 21218

Related projects


NIH 2002 R37 GM	Bioinorganic Copper Coordination Chemistry Karlin, Kenneth D. / Johns Hopkins University	$302,886
NIH 2001 R37 GM	Bioinorganic Copper Coordination Chemistry Karlin, Kenneth D. / Johns Hopkins University	$294,063
NIH 2000 R37 GM	Bioinorganic Copper Coordination Chemistry Karlin, Kenneth D. / Johns Hopkins University	$285,499
NIH 1999 R37 GM	Bioinorganic Copper Coordination Chemistry Karlin, Kenneth D. / Johns Hopkins University
NIH 1998 R37 GM	Bioinorganic Copper Coordination Chemistry Karlin, Kenneth D. / Johns Hopkins University
NIH 1997 R37 GM	Bioinorganic Copper Coordination Chemistry Karlin, Kenneth D. / Johns Hopkins University
NIH 1996 R37 GM	Bioinorganic Copper Coordination Chemistry Karlin, Kenneth D. / Johns Hopkins University
NIH 1995 R37 GM	Bioinorganic Copper Coordination Chemistry Karlin, Kenneth D. / Johns Hopkins University
NIH 1994 R37 GM	Bioinorganic Copper Coordination Chemistry Karlin, Kenneth D. / Johns Hopkins University
NIH 1993 R37 GM	Bioinorganic Copper Coordination Chemistry Karlin, Kenneth D. / Johns Hopkins University

Publications

Bhadra, Mayukh; Lee, Jung Yoon C; Cowley, Ryan E et al. (2018) Intramolecular Hydrogen Bonding Enhances Stability and Reactivity of Mononuclear Cupric Superoxide Complexes. J Am Chem Soc 140:9042-9045

López, Isidoro; Cao, Rui; Quist, David A et al. (2017) Direct Determination of Electron-Transfer Properties of Dicopper-Bound Reduced Dioxygen Species by a Cryo-Spectroelectrochemical Approach. Chemistry 23:18314-18319

Cao, Rui; Elrod, Lee Taylor; Lehane, Ryan L et al. (2016) A Peroxynitrite Dicopper Complex: Formation via Cu-NO and Cu-O2 Intermediates and Reactivity via O-O Cleavage Chemistry. J Am Chem Soc 138:16148-16158

Liu, Jeffrey J; Diaz, Daniel E; Quist, David A et al. (2016) Copper(I)-Dioxygen Adducts and Copper Enzyme Mechanisms. Isr J Chem 56:9-10

Garcia-Bosch, Isaac; Cowley, Ryan E; Díaz, Daniel E et al. (2016) Dioxygen Activation by a Macrocyclic Copper Complex Leads to a Cu2O2 Core with Unexpected Structure and Reactivity. Chemistry 22:5133-7

Cao, Rui; Saracini, Claudio; Ginsbach, Jake W et al. (2016) Peroxo and Superoxo Moieties Bound to Copper Ion: Electron-Transfer Equilibrium with a Small Reorganization Energy. J Am Chem Soc 138:7055-66

Kim, Sunghee; Lee, Jung Yoon; Cowley, Ryan E et al. (2015) A N3S(thioether)-ligated Cu(II)-superoxo with enhanced reactivity. J Am Chem Soc 137:2796-9

Lee, Jung Yoon; Karlin, Kenneth D (2015) Elaboration of copper-oxygen mediated C-H activation chemistry in consideration of future fuel and feedstock generation. Curr Opin Chem Biol 25:184-93

Kim, Sunghee; Ginsbach, Jake W; Lee, Jung Yoon et al. (2015) Amine oxidative N-dealkylation via cupric hydroperoxide Cu-OOH homolytic cleavage followed by site-specific fenton chemistry. J Am Chem Soc 137:2867-74

Kim, Sunghee; Ginsbach, Jake W; Billah, A Imtiaz et al. (2014) Tuning of the copper-thioether bond in tetradentate N?S(thioether) ligands; O-O bond reductive cleavage via a [Cu(II)?(?-1,2-peroxo)]²?/[Cu(III)?(?-oxo)?]²? equilibrium. J Am Chem Soc 136:8063-71

Showing the most recent 10 out of 88 publications

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