Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37GM030902-15
Application #
2021913
Study Section
Molecular and Cellular Biophysics Study Section (BBCA)
Project Start
1982-08-01
Project End
1998-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
U.S. Naval Research Laboratory
Department
Type
DUNS #
020060658
City
Washington
State
DC
Country
United States
Zip Code
20375

  Publications

Karle, Isabella L; Huang, Lulu; Venkateshwarlu, Punna et al. (2009) SUBTLE CONTROL IN SOLUTION AND CRYSTAL STRUCTURES WITH WEAK HYDROGEN BONDS: THE UNUSUAL PROFILE OF DIMETHYL 3, 12-DIOXO-7, 8 DITHIA 4, 11-DIAZABICYCLO[12.2.2]OCTADECA-1(16), 14, 17-TRIENE 5, 10-DICARBOXYLATE (TDA1). Heterocycles 79:471-486
Huang, Lulu; Massa, Lou; Karle, Isabella et al. (2009) Calculation of strong and weak interactions in TDA1 and RangDP52 by the kernel energy method. Proc Natl Acad Sci U S A 106:3664-9
Karle, Isabella L; Ranganathan, Darshan; Kumar, Mittapalli Gopi et al. (2008) Design, synthesis, conformational and membrane ion transport studies of proline-adamantane hybrid cyclic depsipeptides. Biopolymers 89:471-8
Karle, Isabella L; Venkateshwarlu, P; Ranganathan, S (2006) A robust hybrid peptide crystal formed with weak hydrogen bonds. Biopolymers 84:502-7
Karle, I L; Ranganathan, D (2005) An asymmetric conformation of 1,3,5-benzene tricarbonyl [Aib4OMe]3. J Pept Res 65:65-70
Roy, Rituparna S; Karle, Isabella L; Raghothama, S et al. (2004) Alpha,beta hybrid peptides: a polypeptide helix with a central segment containing two consecutive beta-amino acid residues. Proc Natl Acad Sci U S A 101:16478-82
Karle, I L; Prasad, S; Balaram, P (2004) A combined extended and helical backbone for Boc-(Ala-Leu-Ac7c-)2-OMe. J Pept Res 63:175-80
Ravindra, Gudihal; Ranganayaki, Rappal S; Raghothama, Srinivasa et al. (2004) Two novel hexadepsipeptides with several modified amino acid residues isolated from the fungus Isaria. Chem Biodivers 1:489-504
Karle, Isabella L; Gopi, Hosahudya N; Balaram, Padmanabhan (2003) Crystal structure of a hydrophobic 19-residue peptide helix containing three centrally located D amino acids. Proc Natl Acad Sci U S A 100:13946-51
Aravinda, Subrayashastry; Shamala, Narayanaswamy; Das, Chittaranjan et al. (2003) Aromatic-aromatic interactions in crystal structures of helical peptide scaffolds containing projecting phenylalanine residues. J Am Chem Soc 125:5308-15

Showing the most recent 10 out of 74 publications