Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37GM033185-15
Application #
2176896
Study Section
Special Emphasis Panel (NSS)
Project Start
1983-08-01
Project End
2000-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost
Name
State University New York Stony Brook
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
804878247
City
Stony Brook
State
NY
Country
United States
Zip Code
11794
Harada, Yoichiro; Li, Hua; Wall, Joseph S et al. (2011) Structural studies and the assembly of the heptameric post-translational translocon complex. J Biol Chem 286:2956-65
Harada, Yoichiro; Li, Hua; Li, Huilin et al. (2009) Oligosaccharyltransferase directly binds to ribosome at a location near the translocon-binding site. Proc Natl Acad Sci U S A 106:6945-9
Li, Hua; Chavan, Manasi; Schindelin, Hermann et al. (2008) Structure of the oligosaccharyl transferase complex at 12 A resolution. Structure 16:432-40
Chavan, Manasi; Lennarz, William (2006) The molecular basis of coupling of translocation and N-glycosylation. Trends Biochem Sci 31:17-20
Chavan, Manasi; Chen, Zhiqiang; Li, Guangtao et al. (2006) Dimeric organization of the yeast oligosaccharyl transferase complex. Proc Natl Acad Sci U S A 103:8947-52
Nita-Lazar, Mihai; Lennarz, William J (2005) Pkc1p modifies CPY* degradation in the ERAD pathway. Biochem Biophys Res Commun 332:357-61
Chavan, Manasi; Yan, Aixin; Lennarz, William J (2005) Subunits of the translocon interact with components of the oligosaccharyl transferase complex. J Biol Chem 280:22917-24
Yan, Aixin; Lennarz, William J (2005) Unraveling the mechanism of protein N-glycosylation. J Biol Chem 280:3121-4
Yan, Aixin; Wu, Elain; Lennarz, William J (2005) Studies of yeast oligosaccharyl transferase subunits using the split-ubiquitin system: topological features and in vivo interactions. Proc Natl Acad Sci U S A 102:7121-6
Yan, Aixin; Lennarz, William J (2005) Two oligosaccharyl transferase complexes exist in yeast and associate with two different translocons. Glycobiology 15:1407-15

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