Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37GM034497-16
Application #
2177455
Study Section
Special Emphasis Panel (NSS)
Project Start
1985-01-01
Project End
1999-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
16
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Texas Sw Medical Center Dallas
Department
Pharmacology
Type
Schools of Medicine
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75390

  Publications

Thomas, Celestine J; Tall, Gregory G; Adhikari, Anirban et al. (2008) Ric-8A catalyzes guanine nucleotide exchange on G alphai1 bound to the GPR/GoLoco exchange inhibitor AGS3. J Biol Chem 283:23150-60
Kumar, Premlata; Wu, Qian; Chambliss, Ken L et al. (2007) Direct Interactions with G alpha i and G betagamma mediate nongenomic signaling by estrogen receptor alpha. Mol Endocrinol 21:1370-80
Gibson, Scott K; Gilman, Alfred G (2006) Gialpha and Gbeta subunits both define selectivity of G protein activation by alpha2-adrenergic receptors. Proc Natl Acad Sci U S A 103:212-7
Krumins, Andrejs M; Gilman, Alfred G (2006) Targeted knockdown of G protein subunits selectively prevents receptor-mediated modulation of effectors and reveals complex changes in non-targeted signaling proteins. J Biol Chem 281:10250-62
Tall, Gregory G; Gilman, Alfred G (2005) Resistance to inhibitors of cholinesterase 8A catalyzes release of Galphai-GTP and nuclear mitotic apparatus protein (NuMA) from NuMA/LGN/Galphai-GDP complexes. Proc Natl Acad Sci U S A 102:16584-9
Malik, Sundeep; Ghosh, Mousumi; Bonacci, Tabetha M et al. (2005) Ric-8 enhances G protein betagamma-dependent signaling in response to betagamma-binding peptides in intact cells. Mol Pharmacol 68:129-36
Krumins, Andrejs M; Barker, Sheryll A; Huang, Chunfa et al. (2004) Differentially regulated expression of endogenous RGS4 and RGS7. J Biol Chem 279:2593-9
Chen, Zhu; Raman, Malavika; Chen, Linda et al. (2003) TAO (thousand-and-one amino acid) protein kinases mediate signaling from carbachol to p38 mitogen-activated protein kinase and ternary complex factors. J Biol Chem 278:22278-83
Tall, Gregory G; Krumins, Andrejs M; Gilman, Alfred G (2003) Mammalian Ric-8A (synembryn) is a heterotrimeric Galpha protein guanine nucleotide exchange factor. J Biol Chem 278:8356-62
Hooks, Shelley B; Waldo, Gary L; Corbitt, James et al. (2003) RGS6, RGS7, RGS9, and RGS11 stimulate GTPase activity of Gi family G-proteins with differential selectivity and maximal activity. J Biol Chem 278:10087-93

Showing the most recent 10 out of 136 publications