Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37GM035332-18
Application #
6609580
Study Section
Special Emphasis Panel (NSS)
Program Officer
Ikeda, Richard A
Project Start
1986-12-01
Project End
2008-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
18
Fiscal Year
2004
Total Cost
$365,908
Indirect Cost

  Institution

Name
University of California Berkeley
Department
Other Basic Sciences
Type
Schools of Earth Sciences/Natur
DUNS #
124726725
City
Berkeley
State
CA
Country
United States
Zip Code
94704

  Publications

Hernandez, Jose A; Phillips, Aaron H; Erbil, W Kaya et al. (2011) A sterile alpha-motif domain in NafY targets apo-NifDK for iron-molybdenum cofactor delivery via a tethered domain. J Biol Chem 286:6321-8
Martínez-Noël, Giselle; Curatti, Leonardo; Hernandez, Jose A et al. (2011) NifB and NifEN protein levels are regulated by ClpX2 under nitrogen fixation conditions in Azotobacter vinelandii. Mol Microbiol 79:1182-93
Soboh, Basem; Boyd, Eric S; Zhao, Dehua et al. (2010) Substrate specificity and evolutionary implications of a NifDK enzyme carrying NifB-co at its active site. FEBS Lett 584:1487-92
Hernandez, Jose A; Curatti, Leonardo; Aznar, Constantino P et al. (2008) Metal trafficking for nitrogen fixation: NifQ donates molybdenum to NifEN/NifH for the biosynthesis of the nitrogenase FeMo-cofactor. Proc Natl Acad Sci U S A 105:11679-84
George, Simon J; Igarashi, Robert Y; Piamonteze, Cinthia et al. (2007) Identification of a Mo-Fe-S cluster on NifEN by Mo K-edge extended X-ray absorption fine structure. J Am Chem Soc 129:3060-1
Curatti, Leonardo; Hernandez, Jose A; Igarashi, Robert Y et al. (2007) In vitro synthesis of the iron-molybdenum cofactor of nitrogenase from iron, sulfur, molybdenum, and homocitrate using purified proteins. Proc Natl Acad Sci U S A 104:17626-31
Hernandez, Jose A; Igarashi, Robert Y; Soboh, Basem et al. (2007) NifX and NifEN exchange NifB cofactor and the VK-cluster, a newly isolated intermediate of the iron-molybdenum cofactor biosynthetic pathway. Mol Microbiol 63:177-92
Soboh, Basem; Igarashi, Robert Y; Hernandez, Jose A et al. (2006) Purification of a NifEN protein complex that contains bound molybdenum and a FeMo-Co precursor from an Azotobacter vinelandii DeltanifHDK strain. J Biol Chem 281:36701-9
Curatti, Leonardo; Brown, Carolyn S; Ludden, Paul W et al. (2005) Genes required for rapid expression of nitrogenase activity in Azotobacter vinelandii. Proc Natl Acad Sci U S A 102:6291-6
Rubio, Luis M; Singer, Steven W; Ludden, Paul W (2004) Purification and characterization of NafY (apodinitrogenase gamma subunit) from Azotobacter vinelandii. J Biol Chem 279:19739-46

Showing the most recent 10 out of 40 publications