Project Start
1978-01-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
19
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Illinois at Chicago
Department
Physiology
Type
Schools of Medicine
DUNS #
121911077
City
Chicago
State
IL
Country
United States
Zip Code
60612
Le, Jamie A; Wilson, Heather M; Shehu, Aurora et al. (2012) Generation of mice expressing only the long form of the prolactin receptor reveals that both isoforms of the receptor are required for normal ovarian function. Biol Reprod 86:86
Shehu, Aurora; Albarracin, Constance; Devi, Y Sangeeta et al. (2011) The stimulation of HSD17B7 expression by estradiol provides a powerful feed-forward mechanism for estradiol biosynthesis in breast cancer cells. Mol Endocrinol 25:754-66
Le, J A; Wilson, H M; Shehu, A et al. (2011) Prolactin activation of the long form of its cognate receptor causes increased visceral fat and obesity in males as shown in transgenic mice expressing only this receptor subtype. Horm Metab Res 43:931-7
Devi, Y Sangeeta; Seibold, Anita M; Shehu, Aurora et al. (2011) Inhibition of MAPK by prolactin signaling through the short form of its receptor in the ovary and decidua: involvement of a novel phosphatase. J Biol Chem 286:7609-18
Bachelot, Anne; Beaufaron, Julie; Servel, Nathalie et al. (2009) Prolactin independent rescue of mouse corpus luteum life span: identification of prolactin and luteinizing hormone target genes. Am J Physiol Endocrinol Metab 297:E676-84
Devi, Y Sangeeta; Shehu, Aurora; Stocco, Carlos et al. (2009) Regulation of transcription factors and repression of Sp1 by prolactin signaling through the short isoform of its cognate receptor. Endocrinology 150:3327-35
Devi, Y Sangeeta; Shehu, Aurora; Halperin, Julia et al. (2009) Prolactin signaling through the short isoform of the mouse prolactin receptor regulates DNA binding of specific transcription factors, often with opposite effects in different reproductive issues. Reprod Biol Endocrinol 7:87
Shehu, Aurora; Mao, Jifang; Gibori, Gil B et al. (2008) Prolactin receptor-associated protein/17beta-hydroxysteroid dehydrogenase type 7 gene (Hsd17b7) plays a crucial role in embryonic development and fetal survival. Mol Endocrinol 22:2268-77
Halperin, Julia; Devi, Sangeeta Y; Elizur, Shai et al. (2008) Prolactin signaling through the short form of its receptor represses forkhead transcription factor FOXO3 and its target gene galt causing a severe ovarian defect. Mol Endocrinol 22:513-22
Li, Feixue; Devi, Y Sangeeta; Bao, Lei et al. (2008) Involvement of cyclin D3, CDKN1A (p21), and BIRC5 (Survivin) in interleukin 11 stimulation of decidualization in mice. Biol Reprod 78:127-33

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