Prenatal and Neonatal Pituitary/Adrenal Function

Rose, James C.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
• Type: Method to Extend Research in Time (MERIT) Award (R37)
• Project #: 5R37HD011210-17
• Application #: 2196792
• Study Section: Special Emphasis Panel (NSS)
• Project Start: 1978-09-29
• Project End: 1998-11-30
• Budget Start: 1995-12-01
• Budget End: 1996-11-30
• Support Year: 17
• Fiscal Year: 1996

Institution

• Name: Wake Forest University Health Sciences
• Department: Obstetrics & Gynecology
• Type: Schools of Medicine
• DUNS #: 041418799
• City: Winston-Salem
• State: NC
• Country: United States
• Zip Code: 27106

Publications

Su, Yixin; Carey, Luke C; Rose, James C et al. (2013) Antenatal glucocorticoid exposure enhances the inhibition of adrenal steroidogenesis by leptin in a sex-specific fashion. Am J Physiol Endocrinol Metab 304:E1404-11

Su, Yixin; Carey, Luke C; Rose, James C et al. (2012) Leptin alters adrenal responsiveness by decreasing expression of ACTH-R, StAR, and P450c21 in hypoxemic fetal sheep. Reprod Sci 19:1075-84

Valego, Nancy K; Rose, James C (2010) A specific CRH antagonist attenuates ACTH-stimulated cortisol secretion in ovine adrenocortical cells. Reprod Sci 17:477-86

Carey, Luke C; Tatter, Stephen B; Rose, James C (2009) Cortisol infusion in late-gestation hypothalamo-pituitary disconnected sheep fetus restores pituitary cell responsiveness to arginine vasopressin. Am J Physiol Endocrinol Metab 296:E300-4

Carey, Luke C; Tatter, Stephen B; Rose, James C (2007) Ontogeny and effects of hypothalamic pituitary disconnection on formation of inositol trisphosphate in fetal sheep pituitary cells. Endocrinology 148:1440-4

Carey, Luke C; Su, Yixin; Valego, Nancy K et al. (2006) Infusion of ACTH stimulates expression of adrenal ACTH receptor and steroidogenic acute regulatory protein mRNA in fetal sheep. Am J Physiol Endocrinol Metab 291:E214-20

Valego, Nancy K; Su, Yixin; Carey, Luke C et al. (2005) Hypothalamic-pituitary disconnection in fetal sheep blocks the peripartum increases in adrenal responsiveness and adrenal ACTH receptor expression. Am J Physiol Regul Integr Comp Physiol 289:R410-R417

Su, Yixin; Carey, Luke C; Valego, Nancy K et al. (2005) Developmental changes in adrenocorticotrophin (ACTH)-induced expression of ACTH receptor and steroid acute regulatory protein mRNA in ovine fetal adrenal cells. J Soc Gynecol Investig 12:416-20

Chen, Kai; Carey, Luke C; Liu, Jingfang et al. (2005) The effect of hypothalamo-pituitary disconnection on the renin-angiotensin system in the late-gestation fetal sheep. Am J Physiol Regul Integr Comp Physiol 288:R1279-87

Wang, J J; Valego, N K; Su, Y et al. (2004) Developmental aspects of ovine adrenal adrenocorticotropic hormone receptor expression. J Soc Gynecol Investig 11:27-35