Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37HD014907-20
Application #
6636787
Study Section
Special Emphasis Panel (NSS)
Program Officer
Yoshinaga, Koji
Project Start
1983-08-01
Project End
2006-03-31
Budget Start
2003-04-01
Budget End
2004-03-31
Support Year
20
Fiscal Year
2003
Total Cost
$358,302
Indirect Cost
Name
University of Medicine & Dentistry of NJ
Department
Obstetrics & Gynecology
Type
Schools of Medicine
DUNS #
617022384
City
Piscataway
State
NJ
Country
United States
Zip Code
08854
Lin, Win; Bernard, Michael P; Cao, Donghui et al. (2007) Follitropin receptors contain cryptic ligand binding sites. Mol Cell Endocrinol 260-262:83-92
Moyle, William R; Lin, Win; Myers, Rebecca V et al. (2005) Models of glycoprotein hormone receptor interaction. Endocrine 26:189-205
Bernard, Michael P; Lin, Win; Myers, Rebecca et al. (2005) Crosslinked bifunctional gonadotropin analogs with reduced efficacy. Mol Cell Endocrinol 233:25-31
Moyle, William R; Xing, Yongna; Lin, Win et al. (2004) Model of glycoprotein hormone receptor ligand binding and signaling. J Biol Chem 279:44442-59
Bernard, Michael P; Lin, Win; Cao, Donghui et al. (2004) Only a portion of the small seatbelt loop in human choriogonadotropin appears capable of contacting the lutropin receptor. J Biol Chem 279:44438-41
Xing, Yongna; Myers, Rebecca V; Cao, Donghui et al. (2004) Glycoprotein hormone assembly in the endoplasmic reticulum: IV. Probable mechanism of subunit docking and completion of assembly. J Biol Chem 279:35458-68
Xing, Yongna; Myers, Rebecca V; Cao, Donghui et al. (2004) Glycoprotein hormone assembly in the endoplasmic reticulum: I. The glycosylated end of human alpha-subunit loop 2 is threaded through a beta-subunit hole. J Biol Chem 279:35426-36
Xing, Yongna; Myers, Rebecca V; Cao, Donghui et al. (2004) Glycoprotein hormone assembly in the endoplasmic reticulum: III. The seatbelt and its latch site determine the assembly pathway. J Biol Chem 279:35449-57
Xing, Yongna; Lin, Win; Jiang, Mei et al. (2004) Use of protein knobs to characterize the position of conserved alpha-subunit regions in lutropin receptor complexes. J Biol Chem 279:44427-37
Xing, Yongna; Myers, Rebecca V; Cao, Donghui et al. (2004) Glycoprotein hormone assembly in the endoplasmic reticulum: II. Multiple roles of a redox sensitive beta-subunit disulfide switch. J Biol Chem 279:35437-48

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