Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37HD016229-23
Application #
6730021
Study Section
Special Emphasis Panel (NSS)
Program Officer
Yoshinaga, Koji
Project Start
1982-03-01
Project End
2008-02-28
Budget Start
2004-03-01
Budget End
2005-02-28
Support Year
23
Fiscal Year
2004
Total Cost
$260,151
Indirect Cost
Name
Baylor College of Medicine
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
051113330
City
Houston
State
TX
Country
United States
Zip Code
77030
Ren, Yi A; Mullany, Lisa K; Liu, Zhilin et al. (2016) Mutant p53 Promotes Epithelial Ovarian Cancer by Regulating Tumor Differentiation, Metastasis, and Responsiveness to Steroid Hormones. Cancer Res 76:2206-18
Ren, Yi A; Liu, Zhilin; Mullany, Lisa K et al. (2016) Growth Arrest Specific-1 (GAS1) Is a C/EBP Target Gene That Functions in Ovulation and Corpus Luteum Formation in Mice. Biol Reprod 94:44
Adams, Jaye; Liu, Zhilin; Ren, Yi Athena et al. (2016) Enhanced Inflammatory Transcriptome in the Granulosa Cells of Women With Polycystic Ovarian Syndrome. J Clin Endocrinol Metab 101:3459-68
Mullany, Lisa K; Wong, Kwong-Kwok; Marciano, David C et al. (2015) Specific TP53 Mutants Overrepresented in Ovarian Cancer Impact CNV, TP53 Activity, Responses to Nutlin-3a, and Cell Survival. Neoplasia 17:789-803
Kawashima, Ikko; Umehara, Takashi; Noma, Noritaka et al. (2014) Targeted disruption of Nrg1 in granulosa cells alters the temporal progression of oocyte maturation. Mol Endocrinol 28:706-21
Zhang, Yin-Li; Xia, Yan; Yu, Chao et al. (2014) CBP-CITED4 is required for luteinizing hormone-triggered target gene expression during ovulation. Mol Hum Reprod 20:850-60
Liu, Zhilin; Castrillon, Diego H; Zhou, Wei et al. (2013) FOXO1/3 depletion in granulosa cells alters follicle growth, death and regulation of pituitary FSH. Mol Endocrinol 27:238-52
Mullany, Lisa K; Liu, Zhilin; King, Erin R et al. (2012) Wild-type tumor repressor protein 53 (Trp53) promotes ovarian cancer cell survival. Endocrinology 153:1638-48
Richards, J S; Fan, H-Y; Liu, Z et al. (2012) Either Kras activation or Pten loss similarly enhance the dominant-stable CTNNB1-induced genetic program to promote granulosa cell tumor development in the ovary and testis. Oncogene 31:1504-20
Richards, JoAnne S; Liu, Zhilin; Kawai, Tomoko et al. (2012) Adiponectin and its receptors modulate granulosa cell and cumulus cell functions, fertility, and early embryo development in the mouse and human. Fertil Steril 98:471-9.e1

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