Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37HD022681-20
Application #
7098816
Study Section
Special Emphasis Panel (NSS)
Program Officer
Tasca, Richard J
Project Start
1987-09-01
Project End
2008-06-30
Budget Start
2006-07-01
Budget End
2008-06-30
Support Year
20
Fiscal Year
2006
Total Cost
$328,306
Indirect Cost
Name
University of Pennsylvania
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Abe, Ken-Ichiro; Funaya, Satoshi; Tsukioka, Dai et al. (2018) Minor zygotic gene activation is essential for mouse preimplantation development. Proc Natl Acad Sci U S A 115:E6780-E6788
Horvat, Filip; Fulka, Helena; Jankele, Radek et al. (2018) Role of Cnot6l in maternal mRNA turnover. Life Sci Alliance 1:e201800084
Franke, Vedran; Ganesh, Sravya; Karlic, Rosa et al. (2017) Long terminal repeats power evolution of genes and gene expression programs in mammalian oocytes and zygotes. Genome Res 27:1384-1394
Mayer, Alexandra; Baran, Vladimir; Sakakibara, Yogo et al. (2016) DNA damage response during mouse oocyte maturation. Cell Cycle 15:546-58
Ma, P; Schultz, R M (2016) HDAC1 and HDAC2 in mouse oocytes and preimplantation embryos: Specificity versus compensation. Cell Death Differ 23:1119-27
Abe, Ken-Ichiro; Yamamoto, Ryoma; Franke, Vedran et al. (2015) The first murine zygotic transcription is promiscuous and uncoupled from splicing and 3' processing. EMBO J 34:1523-37
Stein, Paula; Rozhkov, Nikolay V; Li, Fan et al. (2015) Essential Role for endogenous siRNAs during meiosis in mouse oocytes. PLoS Genet 11:e1005013
Ma, Pengpeng; de Waal, Eric; Weaver, Jamie R et al. (2015) A DNMT3A2-HDAC2 Complex Is Essential for Genomic Imprinting and Genome Integrity in Mouse Oocytes. Cell Rep 13:1552-60
Ma, Jun; Fukuda, Yusuke; Schultz, Richard M (2015) Mobilization of Dormant Cnot7 mRNA Promotes Deadenylation of Maternal Transcripts During Mouse Oocyte Maturation. Biol Reprod 93:48
Svoboda, Petr; Franke, Vedran; Schultz, Richard M (2015) Sculpting the Transcriptome During the Oocyte-to-Embryo Transition in Mouse. Curr Top Dev Biol 113:305-49

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