Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37HL028935-28
Application #
2216364
Study Section
Special Emphasis Panel (NSS)
Project Start
1982-02-01
Project End
1997-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
28
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Kovacs, A; Weber, M L; Burns, L J et al. (1996) Cytoplasmic sequestration of p53 in cytomegalovirus-infected human endothelial cells. Am J Pathol 149:1531-9
Balla, J; Nath, K A; Balla, G et al. (1995) Endothelial cell heme oxygenase and ferritin induction in rat lung by hemoglobin in vivo. Am J Physiol 268:L321-7
Paller, M S; Jacob, H S (1994) Cytochrome P-450 mediates tissue-damaging hydroxyl radical formation during reoxygenation of the kidney. Proc Natl Acad Sci U S A 91:7002-6
Jacob, H S (1994) Newly recognized causes of atherosclerosis: the role of microorganisms and of vascular iron overload. J Lab Clin Med 123:808-16
Belcher, J D; Balla, J; Balla, G et al. (1993) Vitamin E, LDL, and endothelium. Brief oral vitamin supplementation prevents oxidized LDL-mediated vascular injury in vitro. Arterioscler Thromb 13:1779-89
Balla, J; Belcher, J D; Balla, G et al. (1993) Oxidized low-density lipoproteins and endothelium: oral vitamin E supplementation prevents oxidized low-density lipoprotein-mediated vascular injury. Trans Assoc Am Physicians 106:128-33
Cermak, J; Balla, J; Jacob, H S et al. (1993) Tumor cell heme uptake induces ferritin synthesis resulting in altered oxidant sensitivity: possible role in chemotherapy efficacy. Cancer Res 53:5308-13
Balla, J; Jacob, H S; Balla, G et al. (1993) Endothelial-cell heme uptake from heme proteins: induction of sensitization and desensitization to oxidant damage. Proc Natl Acad Sci U S A 90:9285-9
Balla, J; Jacob, H S; Balla, G et al. (1992) Endothelial cell heme oxygenase and ferritin induction by heme proteins: a possible mechanism limiting shock damage. Trans Assoc Am Physicians 105:1-6
Jacob, H S; Visser, M; Key, N S et al. (1992) Herpes virus infection of endothelium: new insights into atherosclerosis. Trans Am Clin Climatol Assoc 103:95-104

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