Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37HL036141-12
Application #
2028237
Study Section
Special Emphasis Panel (NSS)
Project Start
1985-09-01
Project End
1999-08-31
Budget Start
1996-09-23
Budget End
1997-08-31
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02115
Frantz, Stefan; Ducharme, Anique; Sawyer, Douglas et al. (2003) Targeted deletion of caspase-1 reduces early mortality and left ventricular dilatation following myocardial infarction. J Mol Cell Cardiol 35:685-94
Fukazawa, Ryuji; Miller, Thomas A; Kuramochi, Yukio et al. (2003) Neuregulin-1 protects ventricular myocytes from anthracycline-induced apoptosis via erbB4-dependent activation of PI3-kinase/Akt. J Mol Cell Cardiol 35:1473-9
Frantz, S; Kelly, R A; Bourcier, T (2001) Role of TLR-2 in the activation of nuclear factor kappaB by oxidative stress in cardiac myocytes. J Biol Chem 276:5197-203
Fischer, T A; Ludwig, S; Flory, E et al. (2001) Activation of cardiac c-Jun NH(2)-terminal kinases and p38-mitogen-activated protein kinases with abrupt changes in hemodynamic load. Hypertension 37:1222-8
Feron, O; Zhao, Y Y; Kelly, R A (1999) The ins and outs of caveolar signaling. m2 muscarinic cholinergic receptors and eNOS activation versus neuregulin and ErbB4 signaling in cardiac myocytes. Ann N Y Acad Sci 874:11-9
Hauptman, P J; Kelly, R A (1999) Digitalis. Circulation 99:1265-70
Feron, O; Han, X; Kelly, R A (1999) Muscarinic cholinergic signaling in cardiac myocytes: dynamic targeting of M2AChR to sarcolemmal caveolae and eNOS activation. Life Sci 64:471-7
Sawyer, D B; Fukazawa, R; Arstall, M A et al. (1999) Daunorubicin-induced apoptosis in rat cardiac myocytes is inhibited by dexrazoxane. Circ Res 84:257-65
Frantz, S; Kobzik, L; Kim, Y D et al. (1999) Toll4 (TLR4) expression in cardiac myocytes in normal and failing myocardium. J Clin Invest 104:271-80
Zhao, Y Y; Feron, O; Dessy, C et al. (1999) Neuregulin signaling in the heart. Dynamic targeting of erbB4 to caveolar microdomains in cardiac myocytes. Circ Res 84:1380-7

Showing the most recent 10 out of 56 publications