Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37HL060025-08
Application #
6910875
Study Section
Special Emphasis Panel (NSS)
Program Officer
Lathrop, David A
Project Start
1998-06-01
Project End
2008-06-30
Budget Start
2005-07-01
Budget End
2006-06-30
Support Year
8
Fiscal Year
2005
Total Cost
$381,250
Indirect Cost

  Institution

Name
University of California Los Angeles
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095

  Publications

John, Scott; Weiss, James N; Ribalet, Bernard (2011) Subcellular localization of hexokinases I and II directs the metabolic fate of glucose. PLoS One 6:e17674
John, Scott A; Ottolia, Michela; Weiss, James N et al. (2008) Dynamic modulation of intracellular glucose imaged in single cells using a FRET-based glucose nanosensor. Pflugers Arch 456:307-22
Xie, Lai-Hua; John, Scott A; Ribalet, Bernard et al. (2008) Phosphatidylinositol-4,5-bisphosphate (PIP2) regulation of strong inward rectifier Kir2.1 channels: multilevel positive cooperativity. J Physiol 586:1833-48
Xie, Lai-Hua; John, Scott A; Ribalet, Bernard et al. (2007) Activation of inwardly rectifying potassium (Kir) channels by phosphatidylinosital-4,5-bisphosphate (PIP2): interaction with other regulatory ligands. Prog Biophys Mol Biol 94:320-35
Ribalet, Bernard; John, Scott A; Xie, Lai-Hua et al. (2006) ATP-sensitive K+ channels: regulation of bursting by the sulphonylurea receptor, PIP2 and regions of Kir6.2. J Physiol 571:303-17
Ribalet, Bernard; John, Scott A; Xie, Lai-Hua et al. (2005) Regulation of the ATP-sensitive K channel Kir6.2 by ATP and PIP(2). J Mol Cell Cardiol 39:71-7
Xie, Lai-Hua; John, Scott A; Ribalet, Bernard et al. (2005) Long polyamines act as cofactors in PIP2 activation of inward rectifier potassium (Kir2.1) channels. J Gen Physiol 126:541-9
John, Scott A; Weiss, James N; Ribalet, Bernard (2005) ATP sensitivity of ATP-sensitive K+ channels: role of the gamma phosphate group of ATP and the R50 residue of mouse Kir6.2. J Physiol 568:931-40
Xie, Lai-Hua; John, Scott A; Ribalet, Bernard et al. (2004) Regulation of gating by negative charges in the cytoplasmic pore in the Kir2.1 channel. J Physiol 561:159-68
Xie, Lai-Hua; John, Scott A; Weiss, James N (2003) Inward rectification by polyamines in mouse Kir2.1 channels: synergy between blocking components. J Physiol 550:67-82

Showing the most recent 10 out of 15 publications