The goal of this Phase II STTR project is to develop automated cervical analysis for use after manual screening of thin layer specimens. Such a quality control (QC) system would help to identify false negative cytology specimens. A novel optoelectronic subsystem would be used to identify regions of interest that would be further analyzed by software based image analysis techniques. The combination of the high speed optoelectronic subsystem and the low cost of a software based imaging system would result in an instrument with the potential to recognize the vast majority of abnormal slides with a minimum overall system costs. By developing a post-screening, quality control device, the design goals of an automated screening system are reduced, and a system could have a simpler path through the complex regulatory system. A highly successful Phase I pilot study has demonstrated the feasibility of the device. In Phase II a working prototype will be designed, constructed and tested on a wide variety of specimens.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Small Business Technology Transfer (STTR) Grants - Phase II (R42)
Project #
2R42CA068829-02
Application #
2009033
Study Section
Special Emphasis Panel (ZRG2-REN (01))
Project Start
1995-09-15
Project End
1999-06-30
Budget Start
1997-07-01
Budget End
1998-06-30
Support Year
2
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Cytyc Corporation
Department
Type
DUNS #
City
Boxborough
State
MA
Country
United States
Zip Code
01719