Feasibility has been demonstrated for NMR tubes made from polymeric materials with novel geometries. These tubes offer greater sensitivity, easier sample recovery, greater flexibility and safety, reduced costs, improved response to magnetic fields, and new sampling possibilities. Sensitivity advantages may reduce the time required for many NMR acquisitions by nearly half. This proposal aims at creating tubes for use in the full range of standard 5 mm NMR probeheads for liquid samples, and for 1 mm nanoprobes. The tubes will be compatible with the most common solvents used in NMR. The project will bring the new designs to market readiness. Subcontractors will receive funding to fabricate materials in configurations that are not standard for industrial plastics, concentrating on improved dimensional specifications. Rigorous Quality Assurance procedures will be designed and implemented. User testing of the new tubes will occur in distinguished academic and pharmaceutical company environments. Almost every component in NMR spectrometers continues to improve, except for sample tubes. ARTech's plastic tubes will change that by improving sensitivity, permitting rapid handling without breakage, and allowing for affordable disposability. These advantages have no offsetting disadvantages and benefit both routine and highly sophisticated spectroscopists.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Small Business Technology Transfer (STTR) Grants - Phase II (R42)
Project #
2R42RR018442-02
Application #
6884452
Study Section
Special Emphasis Panel (ZRG1-SSS-6 (10))
Program Officer
Swain, Amy L
Project Start
2003-05-01
Project End
2007-02-28
Budget Start
2005-03-01
Budget End
2006-02-28
Support Year
2
Fiscal Year
2005
Total Cost
$394,906
Indirect Cost
Name
Advanced Resonance Technologies, Inc
Department
Type
DUNS #
956874853
City
Syracuse
State
NY
Country
United States
Zip Code
13244