Breast carcinoma is the leading cause of cancer in women in the U.S. It is well known that if breast cancer is detected when the tumor is small and axillary nodes are not involved, the survival rate is very high. However, if the cancer has spread with time, the survival rate drops significantly. Early detection of breast tumors is therefore critical to the successful treatment of breast cancer and significant reduction in the breast mammography (ACS, Shapiro, Tabar). X-ray mammography is currently performed using a film-screen system and while it has shown good success in detecting early stage, clinically occult breast cancer (ACS, Kopans), the film-screen detector has limited latitude and dynamic range (Nishikawa.) Its performance is also affected by trade-off between detection efficiency and spatial resolution due to increased light spreading in thicker screens which are more efficient in stopping X-rays. In view of these limitations, we plan to explore a novel digital imaging detector for mammography.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Small Business Innovation Research Grants (SBIR) - Phase I (R43)
Project #
5R43CA099104-02
Application #
6723760
Study Section
Special Emphasis Panel (ZCA1-SRRB-9 (O1))
Program Officer
Baker, Houston
Project Start
2003-04-01
Project End
2005-12-31
Budget Start
2004-04-01
Budget End
2005-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$111,477
Indirect Cost
Name
Radiation Monitoring Devices, Inc.
Department
Type
DUNS #
073804411
City
Watertown
State
MA
Country
United States
Zip Code
02472