Research is proposed for the development of a computer-based expert radiology assistant to aid in the diagnosis of breast cancer using clinical findings, x-ray mammograms, and ultrasound images as input data. Based upon encouraging feasibility results which demonstrated that the Phase I prototype system produced interpretations comparable to expert radiologists, it is proposed to extend the system to more complex diagnostic situations, to incorporate a data base for statistical analysis of mammographic data, to optimize the diagnostic rules, to refine the methods of combining evidence, to improve the user interface, and to investigate the role of objective image analysis.
Specific aims of Phase II are designed to provide experimental evidence to determine the role of expert system technology in breast cancer diagnosis, training of residents, management and reporting of examination data, and assistance in detecting and quantifying of abnormalities. The resulting expert system will be extensively tested, both retrospectively and prospectively, using clinical data to evaluate the practically attainable diagnostic accuracy, overall clinical utility, and potential for commercialization.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Small Business Innovation Research Grants (SBIR) - Phase II (R44)
Project #
2R44CA045915-02A1
Application #
3506662
Study Section
Special Emphasis Panel (SSS (B))
Project Start
1987-09-30
Project End
1993-03-31
Budget Start
1991-04-16
Budget End
1992-03-31
Support Year
2
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Xdata Corporation
Department
Type
DUNS #
City
Indianapolis
State
IN
Country
United States
Zip Code
46220