Present orthopedic and dental implant devices use metal alloy systems to align, support and minimize movement of a fractured bone until healing occurs. These devices have several inherent problems which can be overcome by using a glass fiber/polymer bioabsorbable composite. This proposal undertakes the investigation of glass compositions for use in bioabsorbable composite construction for metal device replacement. Composite construction will be achieved by using a polymer system of known bioabsorbable properties and combining it with developed bioabsorbable glass fibers. These fibers will have a specific dissolution rate controlled by their composition. The addition of metal oxides and/or nitrogen to the starting glass system will be used to achieve the needed dissolution rate.

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Small Business Innovation Research Grants (SBIR) - Phase II (R44)
Project #
5R44DE008877-03
Application #
3507231
Study Section
Special Emphasis Panel (SRC (04))
Project Start
1991-02-15
Project End
1993-02-14
Budget Start
1992-02-15
Budget End
1993-02-14
Support Year
3
Fiscal Year
1992
Total Cost
Indirect Cost
Name
MO-Sci Corporation
Department
Type
DUNS #
City
Rolla
State
MO
Country
United States
Zip Code
65401