The goal of this Phase II program is to design and develop an innovative, new actuator, combining FMT's concepts of the """"""""magscrew"""""""" and """"""""magspring"""""""" to produce a highly efficient, long-lived, compact actuating system optimized for ventricle assist devices (VADs). The magscrew, which has already been successfully demonstrated in a total artificial heart actuator, offers many advantages as a driver for implanted blood pumps; namely compactness, reduced wear and fatigue, and nearly lossless conversion of rotational motion to translational actuation. The addition of the magspring is specific to VAD applications. With only one pumping chamber, the return stroke of the actuator is used to store energy in a magspring and, thus, reduce the physical size and motor power losses of the actuator. The magspring concept was successfully validated in Phase I, and results in a rugged, efficient VAD. The Phase II specific aims are to: 1) construct a final, optimized VAD design integrating the magscrew/magspring actuator and a CCF biolized blood pump, 2) develop a prototype controller for the VAD system, 3) perform in vitro endurance tests of the VAD system; and 4) perform in vivo tests of the VAD system in calves.

Proposed Commercial Applications

As a consequence of this research effort, a very long-lived, reliable VAD - one with a 108-mm diameter, a 58-mm thickness, and a 950-g weight - will be available to the permanent implant market. This market has been estimated to include 30,000 candidates per year, according to a 1991 report published by the Institute of Medicine. A sufficiently safe, effective VAD could have a market as large as 200,000 cases per year.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Small Business Innovation Research Grants (SBIR) - Phase II (R44)
Project #
5R44HL059087-03
Application #
6389760
Study Section
Special Emphasis Panel (ZRG1-SSS-W (26))
Program Officer
Altieri, Frank
Project Start
1999-05-15
Project End
2002-10-31
Budget Start
2001-08-01
Budget End
2002-10-31
Support Year
3
Fiscal Year
2001
Total Cost
$565,020
Indirect Cost
Name
Foster-Miller Technologies, Inc.
Department
Type
DUNS #
137357435
City
Albany
State
NY
Country
United States
Zip Code
12205