Currently in the United States, approximately one million people use Home Oxygen Therapy (HOT), and yearly expenditures on HOT exceed 1.5 billion dollars. Most HOT patients use in-situ oxygen generation systems, and the majority of these systems are based on Molecular Sieve Oxygen Generator (MSOG) technology. MSOG systems are sub-optimal in that they are noisy, unreliable, heavy, and expensive, and the purity of the oxygen product degrades with time. The objective of the proposed program is to eliminate the problems associated with MSOGs and reduce HOT costs by developing a Ceramic Oxygen Generating System (COGS). COGS are completely solid-state devices consisting of an oxygen-conducting ceramic membrane across which oxygen ions flow when a differential voltage is applied. COGS do not require a compressor like a MSOG and, thereby, improve reliability and cost. COGS can consistently provide high-purity oxygen (>99%). In Phase I, Create developed and demonstrated an approach for producing thin, non-self-supporting oxygen ion conducting membranes using a proprietary process, the key to a commercially superior COGS, and a conceptual design for a 4 slpm, single-user COGS was developed. In Phase II, we will develop a prototype unit and refine the manufacturing processes to decrease cost.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Small Business Innovation Research Grants (SBIR) - Phase II (R44)
Project #
5R44HL063599-03
Application #
6918033
Study Section
Special Emphasis Panel (ZRG1-SSS-8 (10))
Program Officer
Croxton, Thomas
Project Start
1999-09-30
Project End
2008-06-30
Budget Start
2005-07-01
Budget End
2008-06-30
Support Year
3
Fiscal Year
2005
Total Cost
$373,077
Indirect Cost
Name
Creare, Inc.
Department
Type
DUNS #
072021041
City
Hanover
State
NH
Country
United States
Zip Code
03755