We are developing means to reduce errors in Dipole Source Localization (DSL). DSL is commonly used to analyze brain waves for clinical and research purposes. It is known from our work and the work of others that the models used to compute the DSL are not perfect, but it is not known how much the imperfect models affect the solutions obtained. Based upon our prior work, and some new concepts, we have developed the DSME (Dipole-Source Model- Error). We have tested its efficacy in spheres, and will do so in headshape models in this project. We will compare errors both by simulations, and also by determining whether the DSL has errors when analyzing evoked-responses from known neural generators. The health-related aspects include the clinical uses of evoked-responses and DSL, and the fact that improvements in the accuracy of the technique will improve these uses.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Small Business Innovation Research Grants (SBIR) - Phase II (R44)
Project #
2R44NS041776-02
Application #
6935085
Study Section
Special Emphasis Panel (ZRG1-BDCN-K (10))
Program Officer
Pancrazio, Joseph J
Project Start
2001-09-01
Project End
2007-04-30
Budget Start
2005-08-01
Budget End
2006-04-30
Support Year
2
Fiscal Year
2005
Total Cost
$506,375
Indirect Cost
Name
Abratech Corporation
Department
Type
DUNS #
624508917
City
Mill Valley
State
CA
Country
United States
Zip Code
94941