Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
High Priority, Short Term Project Award (R56)
Project #
1R56DK073990-01A1
Application #
7269141
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Jones, Teresa L Z
Project Start
2006-09-15
Project End
2008-08-31
Budget Start
2006-09-15
Budget End
2007-08-31
Support Year
1
Fiscal Year
2006
Total Cost
$252,000
Indirect Cost
Name
University of Iowa
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
062761671
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Stavniichuk, Roman; Shevalye, Hanna; Lupachyk, Sergey et al. (2014) Peroxynitrite and protein nitration in the pathogenesis of diabetic peripheral neuropathy. Diabetes Metab Res Rev 30:669-78
Davidson, Eric P; Coppey, Lawrence J; Kardon, Randy H et al. (2014) Differences and similarities in development of corneal nerve damage and peripheral neuropathy and in diet-induced obesity and type 2 diabetic rats. Invest Ophthalmol Vis Sci 55:1222-30
Stavniichuk, Roman; Obrosov, Alexander A; Drel, Viktor R et al. (2013) 12/15-Lipoxygenase inhibition counteracts MAPK phosphorylation in mouse and cell culture models of diabetic peripheral neuropathy. J Diabetes Mellitus 3:
Lupachyk, Sergey; Watcho, Pierre; Shevalye, Hanna et al. (2013) Na+/H+ exchanger 1 inhibition reverses manifestation of peripheral diabetic neuropathy in type 1 diabetic rats. Am J Physiol Endocrinol Metab 305:E396-404
Lamping, K G; Nuno, D W; Coppey, L J et al. (2013) Modification of high saturated fat diet with n-3 polyunsaturated fat improves glucose intolerance and vascular dysfunction. Diabetes Obes Metab 15:144-52
Davidson, Eric P; Coppey, Lawrence J; Yorek, Mark A (2012) Early loss of innervation of cornea epithelium in streptozotocin-induced type 1 diabetic rats: improvement with ilepatril treatment. Invest Ophthalmol Vis Sci 53:8067-74
Coppey, Lawrence J; Holmes, Amey; Davidson, Eric P et al. (2012) Partial replacement with menhaden oil improves peripheral neuropathy in high-fat-fed low-dose streptozotocin type 2 diabetic rat. J Nutr Metab 2012:950517
Coppey, Lawrence; Lu, Bao; Gerard, Craig et al. (2012) Effect of Inhibition of Angiotensin-Converting Enzyme and/or Neutral Endopeptidase on Neuropathy in High-Fat-Fed C57Bl/6J Mice. J Obes 2012:326806
Davidson, Eric P; Coppey, Lawrence J; Holmes, Amey et al. (2012) Changes in corneal innervation and sensitivity and acetylcholine-mediated vascular relaxation of the posterior ciliary artery in a type 2 diabetic rat. Invest Ophthalmol Vis Sci 53:1182-7
Davidson, Eric P; Coppey, Lawrence J; Holmes, Amey et al. (2012) Effect of inhibition of angiotensin converting enzyme and/or neutral endopeptidase on vascular and neural complications in high fat fed/low dose streptozotocin-diabetic rats. Eur J Pharmacol 677:180-7

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