Abstract

The goal of this interdisciplinary training program is to train future leaders in Regenerative Medicine. The new discipline of Regenerative Medicine has arisen at the intersection of the frontiers of research in Developmental Biology, Bioengineering, and Clinical Medicine. This Program is truly interdisciplinary in nature and will expose trainees to Developmental Biology, Bioengineering, and the clinical consequences of tissue deficiencies/dysfunction in areas directly pertinent to each trainee's research. This interdisciplinary training program draws on the expertise of faculty from three schools at Stanford University: the School of Humanities and Sciences, the School of Engineering, and the School of Medicine. The Program will train students at two levels: predoctoral and postdoctoral. Each trainee will have a preceptor in whose laboratory he/she will spend the vast majority of their time, and a co-mentor representing a disparate scientific discipline. Predoctoral and Postdoctoral Committees will oversee the selection and monitoring of their respective trainees. Once in the program, the trainees will receive complementary training in the areas with which they have no previous experience. For example, a predoctoral candidate in Developmental Biology will take courses in Bioengineering. Unless trainees already have an MD degree, they will undertake a two-week clinical immersion rotation to expose them to the consequences of organ and tissue deficiencies/dysfunction in areas directly related to their research. In addition to their scientific training, trainees will acquire the leadership skills necessary to direct interdisciplinary research groups in the future. Finally, because our trainees will have an interdisciplinary education that includes Developmental Biology, Bioengineering, and Clinical Medicine, it is anticipated that they will contribute to the development of novel therapies to regenerate, repair, and replace deficient or dysfunctional tissue and organs.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Interdisciplinary Regular Research Training Award (R90)
Project #
5R90DK071508-05
Application #
7483632
Study Section
Special Emphasis Panel (ZDK1-GRB-3 (O1))
Program Officer
Bishop, Terry Rogers
Project Start
2004-09-30
Project End
2009-11-30
Budget Start
2008-08-01
Budget End
2009-11-30
Support Year
5
Fiscal Year
2008
Total Cost
$125,640
Indirect Cost

  Institution

Name
Stanford University
Department
Surgery
Type
Schools of Medicine
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94305

  Publications

Shields, Alicia R; Spence, Allyson C; Yamashita, Yukiko M et al. (2014) The actin-binding protein profilin is required for germline stem cell maintenance and germ cell enclosure by somatic cyst cells. Development 141:73-82
Draper, Christine E; Quon, Andrew; Fredericson, Michael et al. (2012) Comparison of MRI and ยน?F-NaF PET/CT in patients with patellofemoral pain. J Magn Reson Imaging 36:928-32
Draper, Christine E; Fredericson, Michael; Gold, Garry E et al. (2012) Patients with patellofemoral pain exhibit elevated bone metabolic activity at the patellofemoral joint. J Orthop Res 30:209-13
Draper, Christine E; Besier, Thor F; Fredericson, Michael et al. (2011) Differences in patellofemoral kinematics between weight-bearing and non-weight-bearing conditions in patients with patellofemoral pain. J Orthop Res 29:312-7
Besier, Thor F; Fredericson, Michael; Gold, Garry E et al. (2009) Knee muscle forces during walking and running in patellofemoral pain patients and pain-free controls. J Biomech 42:898-905
Keenan, Kathryn E; Kourtis, Lampros C; Besier, Thor F et al. (2009) New resource for the computation of cartilage biphasic material properties with the interpolant response surface method. Comput Methods Biomech Biomed Engin 12:415-22
Draper, Christine E; Besier, Thor F; Santos, Juan M et al. (2009) Using real-time MRI to quantify altered joint kinematics in subjects with patellofemoral pain and to evaluate the effects of a patellar brace or sleeve on joint motion. J Orthop Res 27:571-7
Draper, Christine E; Santos, Juan M; Kourtis, Lampros C et al. (2008) Feasibility of using real-time MRI to measure joint kinematics in 1.5T and open-bore 0.5T systems. J Magn Reson Imaging 28:158-66
Besier, Thor F; Gold, Garry E; Delp, Scott L et al. (2008) The influence of femoral internal and external rotation on cartilage stresses within the patellofemoral joint. J Orthop Res 26:1627-35
Draper, C E; Besier, T F; Gold, G E et al. (2006) Is cartilage thickness different in young subjects with and without patellofemoral pain? Osteoarthritis Cartilage 14:931-7

Showing the most recent 10 out of 11 publications